Adenovirus structure: what is new?
Adenoviruses are large (~ 950 Å) and complex non-enveloped, dsDNA icosahedral viruses.
They have a pseudo-T= 25 triangulation number with at least 12 different proteins …
They have a pseudo-T= 25 triangulation number with at least 12 different proteins …
Adenovirus core proteins: structure and function
S Kulanayake, SK Tikoo - Viruses, 2021 - mdpi.com
Adenoviruses have served as a model for investigating viral-cell interactions and
discovering different cellular processes, such as RNA splicing and DNA replication. In …
discovering different cellular processes, such as RNA splicing and DNA replication. In …
Human adenovirus gene expression and replication is regulated through dynamic changes in nucleoprotein structure throughout infection
MR Jennings, RJ Parks - Viruses, 2023 - mdpi.com
Human adenovirus (HAdV) is extremely common and can rapidly spread in confined
populations such as daycare centers, hospitals, and retirement homes. Although HAdV …
populations such as daycare centers, hospitals, and retirement homes. Although HAdV …
Adenovirus core protein V reinforces the capsid and enhances genome release from disrupted particles
Out of the three core proteins in human adenovirus, protein V is believed to connect the
inner capsid surface to the outer genome layer. Here, we explored mechanical properties …
inner capsid surface to the outer genome layer. Here, we explored mechanical properties …
[HTML][HTML] Adenovirus–a blueprint for gene delivery
Highlights•Stability and built-in weaknesses are emergent properties of adenovirus particles
and key for gene delivery.•Entry is a gain of function process where the virion uncoats in a …
and key for gene delivery.•Entry is a gain of function process where the virion uncoats in a …
Adenovirus entry: Stability, uncoating, and nuclear import
UF Greber, M Suomalainen - Molecular Microbiology, 2022 - Wiley Online Library
Adenoviruses (AdVs) are widespread in vertebrates. They infect the respiratory and
gastrointestinal tracts, the eyes, heart, liver, and kidney, and are lethal to …
gastrointestinal tracts, the eyes, heart, liver, and kidney, and are lethal to …
Monitoring SARS-CoV-2 surrogate TGEV individual virions structure survival under harsh physicochemical environments
Effective airborne transmission of coronaviruses via liquid microdroplets requires a virion
structure that must withstand harsh environmental conditions. Due to the demanding …
structure that must withstand harsh environmental conditions. Due to the demanding …
Dynamic competition for hexon binding between core protein VII and lytic protein VI promotes adenovirus maturation and entry
M Hernando-Pérez… - Proceedings of the …, 2020 - National Acad Sciences
Adenovirus minor coat protein VI contains a membrane-disrupting peptide that is inactive
when VI is bound to hexon trimers. Protein VI must be released during entry to ensure …
when VI is bound to hexon trimers. Protein VI must be released during entry to ensure …
The Adenovirus Death Protein–a small membrane protein controls cell lysis and disease
F Georgi, UF Greber - FEBS letters, 2020 - Wiley Online Library
Human adenoviruses (HAdVs) cause widespread acute and persistent infections. Infections
are usually mild and controlled by humoral and cell‐based immunity. Reactivation of …
are usually mild and controlled by humoral and cell‐based immunity. Reactivation of …
[HTML][HTML] Seeing and touching adenovirus: Complementary approaches for understanding assembly and disassembly of a complex virion
Highlights•Cryo-EM has solved the structure of various adenovirus capsids, but not of the
core.•AFM probes biomechanics and induces/monitors disassembly of individual …
core.•AFM probes biomechanics and induces/monitors disassembly of individual …