The mycobacterial cell envelope—a moving target

CL Dulberger, EJ Rubin, CC Boutte - Nature Reviews Microbiology, 2020 - nature.com
Mycobacterium tuberculosis, the leading cause of death due to infection, has a dynamic and
immunomodulatory cell envelope. The cell envelope structurally and functionally varies …

Mycobacterium tuberculosis-macrophage interaction: Molecular updates

H Bo, UAE Moure, Y Yang, J Pan, L Li… - Frontiers in cellular …, 2023 - frontiersin.org
Mycobacterium tuberculosis (Mtb), the causative agent of Tuberculosis (TB), remains a
pathogen of great interest on a global scale. This airborne pathogen affects the lungs, where …

Mycolic acids: structures, biosynthesis, and beyond

H Marrakchi, MA Lanéelle, M Daffé - Chemistry & biology, 2014 - cell.com
Mycolic acids are major and specific lipid components of the mycobacterial cell envelope
and are essential for the survival of members of the genus Mycobacterium that contains the …

Dissecting the mycobacterial cell envelope and defining the composition of the native mycomembrane

L Chiaradia, C Lefebvre, J Parra, J Marcoux… - Scientific reports, 2017 - nature.com
The mycobacterial envelope is unique, containing the so-called mycomembrane (MM)
composed of very-long chain fatty acids, mycolic acids (MA). Presently, the molecular …

Virulence factors of the Mycobacterium tuberculosis complex

MA Forrellad, LI Klepp, A Gioffré, J Sabio y Garcia… - Virulence, 2013 - Taylor & Francis
The Mycobacterium tuberculosis complex (MTBC) consists of closely related species that
cause tuberculosis in both humans and animals. This illness, still today, remains to be one of …

Antibiotic resistance mechanisms in M. tuberculosis: an update

L Nguyen - Archives of toxicology, 2016 - Springer
Abstract Treatment of tuberculosis (TB) has been a therapeutic challenge because of not
only the naturally high resistance level of Mycobacterium tuberculosis to antibiotics but also …

Assembly of the mycobacterial cell wall

M Jankute, JAG Cox, J Harrison… - Annual review of …, 2015 - annualreviews.org
Mycobacterium tuberculosis remains one of the most successful bacterial pathogens,
claiming over 1.3 million lives worldwide in 2013. The emergence of multidrug-resistant and …

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

ST Cole, R Brosch, J Parkhill, T Garnier, C Churcher… - Nature, 1998 - nature.com
As a result of an error during film output, Table 1 was published with some symbols missing.
The correct version can be found at http://www. sanger. ac. uk and is reproduced again here …

Mycobacterial cell wall biosynthesis: a multifaceted antibiotic target

KA Abrahams, GS Besra - Parasitology, 2018 - cambridge.org
Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis (TB), is recognized
as a global health emergency as promoted by the World Health Organization. Over 1 million …

New insights on trehalose: a multifunctional molecule

AD Elbein, YT Pan, I Pastuszak, D Carroll - Glycobiology, 2003 - academic.oup.com
Trehalose is a nonreducing disaccharide in which the two glucose units are linked in an α, α-
1, 1-glycosidic linkage. This sugar is present in a wide variety of organisms, including …