Wireless technologies in flexible and wearable sensing: from materials design, system integration to applications

L Kong, W Li, T Zhang, H Ma, Y Cao, K Wang… - Advanced …, 2024 - Wiley Online Library
Wireless and wearable sensors attract considerable interest in personalized healthcare by
providing a unique approach for remote, noncontact, and continuous monitoring of various …

Polymeric in situ forming depots for long-acting drug delivery systems

AK Pandya, LK Vora, C Umeyor, D Surve… - Advanced Drug Delivery …, 2023 - Elsevier
Polymeric in situ forming depots have emerged as highly promising drug delivery systems
for long-acting applications. Their effectiveness is attributed to essential characteristics such …

In Situ Forming, Enzyme-Responsive Peptoid-Peptide Hydrogels: An Advanced Long-Acting Injectable Drug Delivery System

SM Coulter, S Pentlavalli, Y An, LK Vora… - Journal of the …, 2024 - ACS Publications
Long-acting drug delivery systems are promising platforms to improve patient adherence to
medication by delivering drugs over sustained periods and removing the need for patients to …

Drug release from in situ forming implants and advances in release testing

X Wang, DJ Burgess - Advanced Drug Delivery Reviews, 2021 - Elsevier
In situ forming implants, defined as liquid formulations that generate solid or semisolid
depots following administration, have shown a range of advantages in drug delivery. This …

Innovative biomaterials for bone tumor treatment and regeneration: tackling postoperative challenges and charting the path forward

Y Wang, H Zhang, H Qiang, M Li, Y Cai… - Advanced …, 2024 - Wiley Online Library
Surgical resection of bone tumors is the primary approach employed in the treatment of
bone cancer. Simultaneously, perioperative interventions, particularly postoperative …

Long-acting injectable PLGA/PLA depots for leuprolide acetate: successful translation from bench to clinic

SR Abulateefeh - Drug Delivery and Translational Research, 2023 - Springer
The excellent properties of polyesters combined with their ease of synthesis and
modification enabled their wide use in the pharmaceutical industry. This has been translated …

In situ forming risperidone implants: Effect of PLGA attributes on product performance

X Wang, Q Bao, R Wang, O Kwok, K Maurus… - Journal of Controlled …, 2023 - Elsevier
Despite the unique advantages of injectable, long-acting in situ forming implant formulations
based on poly (lactide-co-glycolide)(PLGA) and N-Methyl-2-Pyrrolidone (NMP), only six …

Burst release from in situ forming PLGA-based implants: 12 effectors and ways of correction

EOО Bakhrushina, PSS Sakharova, PDD Konogorova… - Pharmaceutics, 2024 - mdpi.com
In modern pharmaceutical technology, modified-release dosage forms, such as in situ
formed implants, are gaining rapidly in popularity. These dosage forms are created based …

Reverse engineering of Perseris and development of compositionally equivalent formulations

X Wang, Q Bao, R Wang, B Wan, Y Wang, B Qin… - International Journal of …, 2023 - Elsevier
Six injectable, long-acting in situ forming implant drug products based on poly (lactide-co-
glycolide)(PLGA) and N-Methyl-2-Pyrrolidone (NMP) are available on the market. However …

[HTML][HTML] An in vitro gel-based system for characterizing and predicting the long-term performance of PLGA in situ forming implants

Z Li, H Mu, SW Larsen, H Jensen… - International Journal of …, 2021 - Elsevier
In situ forming implants are exposed to an extracellular matrix resembling a gel rather than
aqueous solution upon subcutaneous administration. The aim of study was to develop a gel …