Aberrant gene expression that drives human cancer can arise from epigenetic
dysregulation. Although much attention has focused on altered activity of transcription …

Gliomas are the most frequent type of tumor in the central nervous system, which exhibit
properties that make their treatment difficult, such as cellular infiltration, heterogeneity, and …

Bladder cancer (BCa), characterized by high invasion, metastasis, recurrence, and
chemoresistance, is one of the most prevalent urologic malignant tumors. Recent studies …

Background Emerging evidence has demonstrated that RNA-binding protein dysregulation
is involved in esophageal squamous cell carcinoma (ESCC) progression. However, the role …

A recent outbreak of Zika virus in Brazil has led to a simultaneous increase in reports of
neonatal microcephaly. Zika targets cerebral neural precursors, a cell population essential …

Background RNA-binding proteins (RBPs) function as master regulators of gene expression.
Alterations in RBP expression and function are often observed in cancer and influence …

Background Functions for RNA-binding proteins in orchestrating plant development and
environmental responses are well established. However, the lack of a genome-wide view of …

The cancer-associated alternative splicing (AS) events generate cancer-related transcripts
which are involved in uncontrolled cell proliferation and drug resistance. However, the key …

Members of the Msi family of RNA-binding proteins have recently emerged as potent
oncoproteins in a range of malignancies. MSI2 is highly expressed in hematopoietic …

Human RNA binding protein Musashi-1 (MSI1) plays a critical role in neural progenitor cells
(NPCs) by binding to various host RNA transcripts. The canonical MSI1 binding site (MBS) …