HPV post-infection microenvironment and cervical cancer

Y Yuan, X Cai, F Shen, F Ma - Cancer Letters, 2021 - Elsevier
Human papillomavirus (HPV) is the most common sexually transmitted virus worldwide.
More than 99% of cervical cancer cases are associated with certain types of HPVs, termed …

Nano-, micro-, and macroscale drug delivery systems for cancer immunotherapy

P Huang, X Wang, X Liang, J Yang, C Zhang, D Kong… - Acta biomaterialia, 2019 - Elsevier
Immunotherapy is moving to the frontier of cancer treatment. Drug delivery systems (DDSs)
have greatly advanced the development of cancer immunotherapeutic regimen and …

Extracellular vesicles and viruses: two intertwined entities

C Moulin, MJF Crupi, CS Ilkow, JC Bell… - International Journal of …, 2023 - mdpi.com
Viruses share many attributes in common with extracellular vesicles (EVs). The cellular
machinery that is used for EV production, packaging of substrates and secretion is also …

The immune microenvironment in human papilloma virus-induced cervical lesions—Evidence for estrogen as an immunomodulator

J Rs - Frontiers in Cellular and Infection Microbiology, 2021 - frontiersin.org
Globally, human papilloma virus (HPV) infection is a common sexually transmitted disease.
However, most of the HPV infections eventually resolve aided by the body's efficient cell …

The host-microbe interplay in human papillomavirus-induced carcinogenesis

R Wakabayashi, Y Nakahama, V Nguyen, JL Espinoza - Microorganisms, 2019 - mdpi.com
Every year nearly half a million new cases of cervix cancer are diagnosed worldwide,
making this malignancy the fourth commonest cancer in women. In 2018, more than 270,000 …

Efficacy of PD-1 blockade in cervical cancer is related to a CD8+FoxP3+CD25+ T-cell subset with operational effector functions despite high immune checkpoint …

AM Heeren, J Rotman, AGM Stam, N Pocorni… - … for immunotherapy of …, 2019 - Springer
Abstract Background Cervical cancer (CxCa) is mainly a locally invading disease that
metastasizes to loco-regional lymph node basins before involving distant organs in more …

Extracellular vesicles in cervical cancer and HPV infection

V Acevedo-Sánchez, RM Rodríguez-Hernández… - Membranes, 2021 - mdpi.com
Since their description, extracellular vesicles (EVs) have shown growing relevance in cancer
progression. These cell structures contain and transfer molecules such as nucleic acids …

Unusual prevalence of high-risk genotypes of human papillomavirus in a group of women with neoplastic lesions and cervical cancer from Central Mexico

RG Campos, A Malacara Rosas, E Gutiérrez Santillán… - PLoS …, 2019 - journals.plos.org
Human papillomavirus has been identified as a main etiological agent in the development of
cervical cancer. HPV 16 and 18 have been reported the most widely prevalent genotypes …

The role of regulatory T cells in pathogenesis and therapy of human papillomavirus-related diseases, especially in cancer

C Ao, K Zeng - Infection, Genetics and Evolution, 2018 - Elsevier
Human papillomavirus (HPV) is the most common sexually transmitted agent in the world. It
can cause condyloma acuminatum, anogenital malignancies, and head and neck cancers …

Identification of significant genes signatures and prognostic biomarkers in cervical squamous carcinoma via bioinformatic data

Y He, S Hu, J Zhong, A Cheng, N Shan - PeerJ, 2020 - peerj.com
Background Cervical squamous cancer (CESC) is an intractable gynecological malignancy
because of its high mortality rate and difficulty in early diagnosis. Several biomarkers have …