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Marek's disease vaccines: a solution for today but a worry for tomorrow?
IM Gimeno - Vaccine, 2008 - Elsevier
Marek's disease (MD) is a lymphoproliferative disease of chickens that, in the absence of
control measures, is capable of causing devastating losses in commercial poultry flocks. MD …
control measures, is capable of causing devastating losses in commercial poultry flocks. MD …
Release of HSV-1 cell-free virions: Mechanisms, regulation, and likely role in human-human transmission
SA Rice - Viruses, 2021 - mdpi.com
Herpes simplex virus type 1, or HSV-1, is a widespread human pathogen that replicates in
epithelial cells of the body surface and then establishes latent infection in peripheral …
epithelial cells of the body surface and then establishes latent infection in peripheral …
Evolution and diversity in human herpes simplex virus genomes
ABSTRACT Herpes simplex virus 1 (HSV-1) causes a chronic, lifelong infection in> 60% of
adults. Multiple recent vaccine trials have failed, with viral diversity likely contributing to …
adults. Multiple recent vaccine trials have failed, with viral diversity likely contributing to …
Sequence variability in clinical and laboratory isolates of herpes simplex virus 1 reveals new mutations
ABSTRACT Herpes simplex virus 1 (HSV-1) is a well-adapted human pathogen that can
invade the peripheral nervous system and persist there as a lifelong latent infection. Despite …
invade the peripheral nervous system and persist there as a lifelong latent infection. Despite …
Herpesvirus telomeric repeats facilitate genomic integration into host telomeres and mobilization of viral DNA during reactivation
Some herpesviruses, particularly lymphotropic viruses such as Marek's disease virus (MDV)
and human herpesvirus 6 (HHV-6), integrate their DNA into host chromosomes. MDV and …
and human herpesvirus 6 (HHV-6), integrate their DNA into host chromosomes. MDV and …
Marek's Disease Viral Interleukin-8 Promotes Lymphoma Formation through Targeted Recruitment of B Cells and CD4+ CD25+ T Cells
Marek's disease virus (MDV) is a cell-associated and highly oncogenic alphaherpesvirus
that infects chickens. During lytic and latent MDV infection, a CXC chemokine termed viral …
that infects chickens. During lytic and latent MDV infection, a CXC chemokine termed viral …
Role of the arginine cluster in the disordered domain of herpes simplex virus 1 UL34 for the recruitment of ESCRT-III for viral primary envelopment
J Arii, K Takeshima, Y Maruzuru, N Koyanagi… - Journal of …, 2022 - journals.asm.org
During the nuclear export of nascent nucleocapsids of herpesviruses, the nucleocapsids
bud through the inner nuclear membrane (INM) by acquiring the INM as a primary envelope …
bud through the inner nuclear membrane (INM) by acquiring the INM as a primary envelope …
[HTML][HTML] Virus and host genomic, molecular, and cellular interactions during Marek's disease pathogenesis and oncogenesis
MC McPherson, ME Delany - Poultry science, 2016 - Elsevier
ABSTRACT Marek's Disease Virus (MDV) is a chicken alphaherpesvirus that causes
paralysis, chronic wasting, blindness, and fatal lymphoma development in infected …
paralysis, chronic wasting, blindness, and fatal lymphoma development in infected …
[HTML][HTML] Enhancement of HSV-1 cell-free virion release by the envelope protein gC
TC Frost, M Salnikov, SA Rice - Virology, 2024 - Elsevier
Glycoprotein C (gC), one of∼ 12 HSV-1 envelope glycoproteins, carries out several
important functions during infection, including the enhancement of virion attachment by …
important functions during infection, including the enhancement of virion attachment by …
Attenuation of a very virulent Marek's disease herpesvirus (MDV) by codon pair bias deoptimization
Codon pair bias deoptimization (CPBD) has enabled highly efficient and rapid attenuation of
RNA viruses. The technique relies on recoding of viral genes by increasing the number of …
RNA viruses. The technique relies on recoding of viral genes by increasing the number of …