Epidemiological data from the Center of Disease Control (CDC) and the World Health
Organization (WHO) statistics in 2017 show that 10.0 million people around the world …

Mycobacterium tuberculosis, which is the aetiological agent of tuberculosis, owes much of its
success as a pathogen to its unique cell wall and unusual mechanism of growth, which …

We face an impending crisis in our ability to treat infectious disease brought about by the
emergence of antibiotic-resistant pathogens and a decline in the development of new …

Mycobacteriophages are viruses that infect mycobacterial hosts. A large number of
mycobacteriophages have been isolated and genomically characterized, providing insights …

Highlights•Mycobacteriales contain a complex, multilayered cell envelope.•Synthesis of the
cell envelope is driven by specific nanomachineries for apical cell elongation and …

M ycobacterium tuberculosis (Mtb) is an aerobic bacterium that persists intracellularly in host
macrophages and has evolved diverse mechanisms to combat and survive oxidative stress …

Reproduction in the bacterial kingdom predominantly occurs through binary fission—a
process in which one parental cell is divided into two similarly sized daughter cells. How cell …

We took a different approach to reviewing the commercial biosensor literature this year by
inviting 22 biosensor users to serve as a review committee. They set the criteria for what to …

Background Sensing and responding to environmental changes is a central aspect of cell
division regulation. Mycobacterium tuberculosis contains eleven Ser/Thr kinases, two of …

Polarized growth in eukaryotes requires polar multiprotein complexes. Here, we establish
that selection and maintenance of cell polarity for growth also requires a dedicated …