Kaposi's sarcoma-associated herpesvirus, the etiological agent of all epidemiological forms of Kaposi's sarcoma
A Jary, M Veyri, A Gothland, V Leducq, V Calvez… - Cancers, 2021 - mdpi.com
Simple Summary Kaposi's sarcoma-associated herpesvirus (KSHV) is one of the seven
oncogenic viruses currently recognized by the International Agency for Research on Cancer …
oncogenic viruses currently recognized by the International Agency for Research on Cancer …
Immune evasion strategies of molluscum contagiosum virus
JL Shisler - Advances in virus research, 2015 - Elsevier
Molluscum contagiosum virus (MCV) is the causative agent of molluscum contagiosum
(MC), the third most common viral skin infection in children, and one of the five most …
(MC), the third most common viral skin infection in children, and one of the five most …
Immunomodulatory drugs target IKZF1-IRF4-MYC axis in primary effusion lymphoma in a cereblon-dependent manner and display synergistic cytotoxicity with BRD4 …
Primary effusion lymphoma (PEL) is an aggressive type of non-Hodgkin lymphoma localized
predominantly in body cavities. Kaposi's sarcoma-associated herpes virus (KSHV) is the …
predominantly in body cavities. Kaposi's sarcoma-associated herpes virus (KSHV) is the …
Gene essentiality landscape and druggable oncogenic dependencies in herpesviral primary effusion lymphoma
Primary effusion lymphoma (PEL) is caused by Kaposi's sarcoma-associated herpesvirus.
Our understanding of PEL is poor and therefore treatment strategies are lacking. To address …
Our understanding of PEL is poor and therefore treatment strategies are lacking. To address …
Development and characterization of a novel luciferase based cytotoxicity assay
H Matta, R Gopalakrishnan, S Choi, R Prakash… - Scientific Reports, 2018 - nature.com
A simple, accurate, sensitive and robust assay that can rapidly and specifically measure the
death of target cells would have applications in many areas of biomedicine and particularly …
death of target cells would have applications in many areas of biomedicine and particularly …
Modulation of virus-induced NF-κB signaling by NEMO coiled coil mimics
Protein-protein interactions featuring intricate binding epitopes remain challenging targets
for synthetic inhibitors. Interactions of NEMO, a scaffolding protein central to NF-κB …
for synthetic inhibitors. Interactions of NEMO, a scaffolding protein central to NF-κB …
Diverse mechanisms evolved by DNA viruses to inhibit early host defenses
In mammalian cells, early defenses against infection by pathogens are mounted through a
complex network of signaling pathways shepherded by immune-modulatory pattern …
complex network of signaling pathways shepherded by immune-modulatory pattern …
CRISPR screens identify novel regulators of cFLIP dependency and ligand-independent, TRAIL-R1-mediated cell death
Kaposi's sarcoma-associated herpesvirus (KSHV) causes primary effusion lymphoma (PEL).
PEL cell lines require expression of the cellular FLICE inhibitory protein (cFLIP) for survival …
PEL cell lines require expression of the cellular FLICE inhibitory protein (cFLIP) for survival …
Narciclasine, an isocarbostyril alkaloid, has preferential activity against primary effusion lymphoma
R Gopalakrishnan, H Matta, S Choi, PM Chaudhary - Scientific Reports, 2020 - nature.com
Primary effusion lymphoma (PEL) is a subtype of non-Hodgkin lymphoma associated with
infection by Kaposi sarcoma-associated herpes virus (KSHV). PEL is an aggressive disease …
infection by Kaposi sarcoma-associated herpes virus (KSHV). PEL is an aggressive disease …
CADM1 is essential for KSHV-encoded vGPCR-and vFLIP-mediated chronic NF-κB activation
R Hunte, P Alonso, R Thomas, CA Bazile… - PLoS …, 2018 - journals.plos.org
Approximately 12% of all human cancers worldwide are caused by infections with
oncogenic viruses. Kaposi's sarcoma herpesvirus/human herpesvirus 8 (KSHV/HHV8) is …
oncogenic viruses. Kaposi's sarcoma herpesvirus/human herpesvirus 8 (KSHV/HHV8) is …