Adult neurogenesis and functional plasticity in neuronal circuits

PM Lledo, M Alonso, MS Grubb - Nature Reviews Neuroscience, 2006 - nature.com
The adult brain is a plastic place. To ensure that the mature nervous system's control of
behaviour is flexible in the face of a varying environment, morphological and physiological …

Neuregulin 1 in neural development, synaptic plasticity and schizophrenia

L Mei, WC **ong - Nature Reviews Neuroscience, 2008 - nature.com
Schizophrenia is a highly debilitating mental disorder that affects∼ 1% of the general
population, yet it continues to be poorly understood. Recent studies have identified …

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

HS Phillips, S Kharbanda, R Chen, WF Forrest… - Cancer cell, 2006 - cell.com
Previously undescribed prognostic subclasses of high-grade astrocytoma are identified and
discovered to resemble stages in neurogenesis. One tumor class displaying neuronal …

NMDAR hypofunction animal models of schizophrenia

G Lee, Y Zhou - Frontiers in molecular neuroscience, 2019 - frontiersin.org
The N-methyl-d-aspartate receptor (NMDAR) hypofunction hypothesis has been proposed to
help understand the etiology and pathophysiology of schizophrenia. This hypothesis was …

Exome sequencing identifies GRIN2A as frequently mutated in melanoma

X Wei, V Walia, JC Lin, JK Teer, TD Prickett, J Gartner… - Nature …, 2011 - nature.com
The incidence of melanoma is increasing more than any other cancer, and knowledge of its
genetic alterations is limited. To systematically analyze such alterations, we performed …

Altered neuregulin 1–erbB4 signaling contributes to NMDA> receptor hypofunction in schizophrenia

CG Hahn, HY Wang, DS Cho, K Talbot, RE Gur… - Nature medicine, 2006 - nature.com
Recent molecular genetics studies implicate neuregulin 1 (NRG1) and its receptor erbB in
the pathophysiology of schizophrenia,,. Among NRG1 receptors, erbB4 is of particular …

Neurogenesis and Alzheimer's disease: at the crossroads

O Lazarov, RA Marr - Experimental neurology, 2010 - Elsevier
While a massive and progressive neuronal loss in specific areas such as the hippocampus
and cortex unequivocally underlies cognitive deterioration and memory loss in Alzheimer's …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Vasculature guides migrating neuronal precursors in the adult mammalian forebrain via brain-derived neurotrophic factor signaling

M Snapyan, M Lemasson, MS Brill, M Blais… - Journal of …, 2009 - Soc Neuroscience
Adult neuronal precursors retain the remarkable capacity to migrate long distances from the
posterior (subventricular zone) to the most anterior [olfactory bulb (OB)] parts of the brain …

Adult neurogenesis and the olfactory system

MC Whitman, CA Greer - Progress in neurobiology, 2009 - Elsevier
Though initially described in the early 1960s, it is only within the past decade that the
concept of continuing adult neurogenesis has gained widespread acceptance. Neuroblasts …