It is widely appreciated that larvae of the nematode Caenorhabditis elegans arrest
development by forming dauer larvae in response to multiple unfavorable environmental …

Pre-RNA splicing is an essential step in generating mature mRNA. RNA trans-splicing
combines two separate pre-mRNA molecules to form a chimeric non-co-linear RNA, which …

Although protein expression is regulated both temporally and spatially, most proteins have
an intrinsic," typical" range of functionally effective abundance levels. These extend from a …

Complex interactions among genetic components often result in variable systemic
performance in designed multigene systems,. Using the bacterial clustered regularly …

Entomopathogenic nematodes (EPNs) are unique parasites due to their symbiosis with
entomopathogenic bacteria and their ability to kill insect hosts quickly after infection. It is …

Animals with compact sensory systems face an encoding problem where a small number of
sensory neurons are required to encode information about its surrounding complex …

About 70% of C. elegans mRNAs are trans-spliced to one of two 22 nucleotide spliced
leaders. SL1 is used to trim off the 5'ends of pre-mRNAs and replace them with the SL1 …

Fluctuations in nutrient availability profoundly impact gene expression. Previous work
revealed postrecruitment regulation of RNA polymerase II (Pol II) during starvation and …

Identification of co-expressed sets of genes (gene modules) is used widely for grou**
functionally related genes during transcriptomic data analysis. An organism-wide atlas of …

Translational efficiency is subject to extensive regulation. However, the factors influencing
such regulation are poorly understood. In Caenorhabditis elegans, 62% of genes are trans …