Ischemia-triggered glutamate excitotoxicity from the perspective of glial cells
D Belov Kirdajova, J Kriska, J Tureckova… - Frontiers in cellular …, 2020 - frontiersin.org
A plethora of neurological disorders shares a final common deadly pathway known as
excitotoxicity. Among these disorders, ischemic injury is a prominent cause of death and …
excitotoxicity. Among these disorders, ischemic injury is a prominent cause of death and …
Understanding the NG2 glial scar after spinal cord injury
AR Hackett, JK Lee - Frontiers in neurology, 2016 - frontiersin.org
NG2 cells, also known as oligodendrocyte progenitor cells, are located throughout the
central nervous system and serve as a pool of progenitors to differentiate into …
central nervous system and serve as a pool of progenitors to differentiate into …
The increased activity of TRPV4 channel in the astrocytes of the adult rat hippocampus after cerebral hypoxia/ischemia
The polymodal transient receptor potential vanilloid 4 (TRPV4) channel, a member of the
TRP channel family, is a calcium-permeable cationic channel that is gated by various stimuli …
TRP channel family, is a calcium-permeable cationic channel that is gated by various stimuli …
Heterogeneity of astrocytes: from development to injury–single cell gene expression
Astrocytes perform control and regulatory functions in the central nervous system;
heterogeneity among them is still a matter of debate due to limited knowledge of their gene …
heterogeneity among them is still a matter of debate due to limited knowledge of their gene …
Astrocyte‐like subpopulation of NG2 glia in the adult mouse cortex exhibits characteristics of neural progenitor cells
L Janeckova, T Knotek, J Kriska, Z Hermanova… - Glia, 2024 - Wiley Online Library
Glial cells expressing neuron‐glial antigen 2 (NG2), also known as oligodendrocyte
progenitor cells (OPCs), play a critical role in maintaining brain health. However, their ability …
progenitor cells (OPCs), play a critical role in maintaining brain health. However, their ability …
NMDA receptors in glial cells: pending questions
Glutamate receptors of the N-methyl-D-aspartate (NMDA) type are involved in many
cognitive processes, including behavior, learning and synaptic plasticity. For a long time …
cognitive processes, including behavior, learning and synaptic plasticity. For a long time …
Wnt/β-Catenin signaling promotes differentiation of ischemia-activated adult neural stem/progenitor cells to neuronal precursors
Modulating endogenous regenerative processes may represent a suitable treatment for
central nervous system (CNS) injuries, such as stroke or trauma. Neural stem/progenitor …
central nervous system (CNS) injuries, such as stroke or trauma. Neural stem/progenitor …
Ionic transporter activity in astrocytes, microglia, and oligodendrocytes during brain ischemia
L Annunziato, F Boscia… - Journal of Cerebral Blood …, 2013 - journals.sagepub.com
Glial cells constitute a large percentage of cells in the nervous system. During recent years,
a large number of studies have critically attributed to glia a new role which no longer reflects …
a large number of studies have critically attributed to glia a new role which no longer reflects …
Transient astrocyte‐like NG2 glia subpopulation emerges solely following permanent brain ischemia
abstract NG2 glia display wide proliferation and differentiation potential under physiological
and pathological conditions. Here, we examined these two features following different types …
and pathological conditions. Here, we examined these two features following different types …
NG2/CSPG4 and progranulin in the posttraumatic glial scar
MKE Schäfer, I Tegeder - Matrix biology, 2018 - Elsevier
Traumatic injury of the central nervous system is one of the leading causes of death and
disability in young adults. Failure of regeneration is caused by autonomous neuronal …
disability in young adults. Failure of regeneration is caused by autonomous neuronal …