Click chemistry: 1, 2, 3‐triazoles as pharmacophores
SG Agalave, SR Maujan… - Chemistry–An Asian …, 2011 - Wiley Online Library
Abstract The copper (I)‐catalyzed 1, 2, 3‐triazole‐forming reaction between azides and
terminal alkynes has become the gold standard of 'click chemistry'due to its reliability …
terminal alkynes has become the gold standard of 'click chemistry'due to its reliability …
Recent researches in triazole compounds as medicinal drugs
C -H. Zhou, Y Wang - Current medicinal chemistry, 2012 - benthamdirect.com
Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole
ring are readily able to bind with a variety of enzymes and receptors in biological system via …
ring are readily able to bind with a variety of enzymes and receptors in biological system via …
Structure-activity relationships (SAR) of triazine derivatives: Promising antimicrobial agents
The emergence of drug resistance has created unmet medical need for the development of
new classes of antibiotics. Innovation of new antibacterial agents with new mode of action …
new classes of antibiotics. Innovation of new antibacterial agents with new mode of action …
Synthesis, in vitro evaluation and molecular docking studies of novel triazine-triazole derivatives as potential α-glucosidase inhibitors
G Wang, Z Peng, J Wang, X Li, J Li - European journal of medicinal …, 2017 - Elsevier
A novel series of triazine-triazole derivatives 7a–7m were synthesized, characterized by 1 H
NMR and evaluated for their α-glucosidase inhibitory activity. All the synthesized …
NMR and evaluated for their α-glucosidase inhibitory activity. All the synthesized …
Synthesis, characterizations, antitumor and antimicrobial evaluations of novel Mn (II) and Cu (II) complexes with NNN-tridentate s-Triazine-Schiff base ligand
The new s-triazine hydrazone, 2, 4-bis (morpholin-4-yl)-6-[(E)-2-[1-(pyridin-2-yl) ethylidene]
hydrazin-1-yl]-1, 3, 5-triazine,(L) ligand was used to synthesize three new metal complexes …
hydrazin-1-yl]-1, 3, 5-triazine,(L) ligand was used to synthesize three new metal complexes …
[PDF][PDF] 1, 2, 4-triazine analogs as novel class of therapeutic agents
R Kumar, TS Sirohi, H Singh, R Yadav… - Mini-Rev. Med …, 2014 - researchgate.net
Abstract: 1, 2, 4-Triazine nucleus is a prominent structural core system present in numerous
pharmacologically active compounds. Till date, various 1, 2, 4-triazine analogs, possesing a …
pharmacologically active compounds. Till date, various 1, 2, 4-triazine analogs, possesing a …
Microwave assisted one pot synthesis of some novel 2, 5-disubstituted 1, 3, 4-oxadiazoles as antifungal agents
Sodium bisulfite has been reported first time for the synthesis of 2, 5-disubstituted 1, 3, 4-
oxadiazole using microwave and conventional method in ethanol–water. The yields …
oxadiazole using microwave and conventional method in ethanol–water. The yields …
Synthesis, biological evaluation, and docking studies of novel 5, 6-diaryl-1, 2, 4-triazine thiazole derivatives as a new class of α-glucosidase inhibitors
G Wang, Z Peng, Z Gong, Y Li - Bioorganic Chemistry, 2018 - Elsevier
Abstract A novel 5, 6-diaryl-1, 2, 4-triazine thiazole derivatives (7a-7q) were synthesized and
characterized by 1 H NMR and 13 C NMR and evaluated for their α-glucosidase inhibitory …
characterized by 1 H NMR and 13 C NMR and evaluated for their α-glucosidase inhibitory …
Synthesis and biological evaluation of novel 1, 2, 4-triazine derivatives bearing carbazole moiety as potent α-glucosidase inhibitors
G Wang, J Wang, D He, X Li, J Li, Z Peng - Bioorganic & Medicinal …, 2016 - Elsevier
Abstract A new series of 1, 2, 4-triazine derivatives bearing carbazole moiety 7a–7p were
designed, synthesized, and evaluated for their α-glucosidase inhibitory activity. The majority …
designed, synthesized, and evaluated for their α-glucosidase inhibitory activity. The majority …
Microwave assisted synthesis of some new fused 1, 2, 4-triazines bearing thiophene moieties with expected pharmacological activity
Rapid and efficient solvent-free synthesis of 4-amino-3-mercapto-6-[2-(2-thienyl) vinyl]-1, 2,
4-triazin-5 (4 H)-one 1 under microwave irradiation is described. Some new fused …
4-triazin-5 (4 H)-one 1 under microwave irradiation is described. Some new fused …