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MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation
The epidemic community-associated methicillin-resistant Staphylococcus aureus (CA-
MRSA) USA300 lineage has recently become a leading cause of hospital-associated …
MRSA) USA300 lineage has recently become a leading cause of hospital-associated …
PcdA promotes orthogonal division plane selection in Staphylococcus aureus
The bacterial pathogen, Staphylococcus aureus, grows by dividing in two alternating
orthogonal planes. How these cell division planes are positioned correctly is not known …
orthogonal planes. How these cell division planes are positioned correctly is not known …
Efflux pump gene amplifications bypass necessity of multiple target mutations for resistance against dual-targeting antibiotic
Antibiotics that have multiple cellular targets theoretically reduce the frequency of resistance
evolution, but adaptive trajectories and resistance mechanisms against such antibiotics are …
evolution, but adaptive trajectories and resistance mechanisms against such antibiotics are …
Staphylococcus aureus adapts to exploit collagen-derived proline during chronic infection
Staphylococcus aureus is a pulmonary pathogen associated with substantial human
morbidity and mortality. As vaccines targeting virulence determinants have failed to be …
morbidity and mortality. As vaccines targeting virulence determinants have failed to be …
SarS is a repressor of Staphylococcus aureus bicomponent pore-forming leukocidins
Staphylococcus aureus is a successful pathogen that produces a wide range of virulence
factors that it uses to subvert and suppress the immune system. These include the …
factors that it uses to subvert and suppress the immune system. These include the …
Recent Advances in Genetic Tools for Acinetobacter baumannii
Acinetobacter baumannii is classified as a top priority pathogen by the World Health
Organization (WHO) because of its widespread resistance to all classes of antibiotics. This …
Organization (WHO) because of its widespread resistance to all classes of antibiotics. This …
Strategies for develo** CRISPR‐based gene editing methods in bacteria
Z Wu, Y Wang, Y Zhang, W Chen, Y Wang… - Small Methods, 2020 - Wiley Online Library
Gene editing is a fundamental technique for the identification of the linkages from genetic
determinants to significant biological phenotypes, and the engineering of industrial strains to …
determinants to significant biological phenotypes, and the engineering of industrial strains to …
Expanding the genetic toolbox for the obligate human pathogen Streptococcus pyogenes
N Lautenschläger, K Schmidt, C Schiffer… - … in Bioengineering and …, 2024 - frontiersin.org
Genetic tools form the basis for the study of molecular mechanisms. Despite many recent
advances in the field of genetic engineering in bacteria, genetic toolsets remain scarce for …
advances in the field of genetic engineering in bacteria, genetic toolsets remain scarce for …
High‐throughput transposon sequencing highlights the cell wall as an important barrier for osmotic stress in methicillin resistant Staphylococcus aureus and …
CF Schuster, DM Wiedemann… - Molecular …, 2020 - Wiley Online Library
Staphylococcus aureus is an opportunistic pathogen that can cause soft tissue infections but
is also a frequent cause of foodborne illnesses. One contributing factor for this food …
is also a frequent cause of foodborne illnesses. One contributing factor for this food …
The major autolysin Atl regulates the virulence of Staphylococcus aureus by controlling the sorting of LukAB
Infections caused by the Gram-positive bacterium Staphylococcus aureus remain a
significant health threat globally. The production of bicomponent pore-forming leukocidins …
significant health threat globally. The production of bicomponent pore-forming leukocidins …