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Epstein–Barr virus and cancer
PJ Farrell - Annual Review of Pathology: Mechanisms of …, 2019 - annualreviews.org
Epstein–Barr virus (EBV) contributes to about 1.5% of all cases of human cancer worldwide,
and viral genes are expressed in the malignant cells. EBV also very efficiently causes the …
and viral genes are expressed in the malignant cells. EBV also very efficiently causes the …
Epstein–Barr virus: more than 50 years old and still providing surprises
It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus, was
discovered. EBV has subsequently been found to be associated with a diverse range of …
discovered. EBV has subsequently been found to be associated with a diverse range of …
The role of Epstein–Barr virus in epithelial malignancies
The close association of Epstein–Barr virus (EBV) infection with non‐keratinizing
nasopharyngeal carcinomas and a subset of gastric carcinomas suggests that EBV infection …
nasopharyngeal carcinomas and a subset of gastric carcinomas suggests that EBV infection …
EBV-positive gastric cancer: current knowledge and future perspectives
K Sun, K Jia, H Lv, SQ Wang, Y Wu, H Lei… - Frontiers in …, 2020 - frontiersin.org
Gastric cancer is the fifth most common malignant tumor and second leading cause of
cancer-related deaths worldwide. With the improved understanding of gastric cancer, a …
cancer-related deaths worldwide. With the improved understanding of gastric cancer, a …
Molecular mechanisms of EBV-driven cell cycle progression and oncogenesis
H Yin, J Qu, Q Peng, R Gan - Medical microbiology and immunology, 2019 - Springer
The early stage of oncogenesis is linked to the disorder of the cell cycle. Abnormal gene
expression often leads to cell cycle disorders, resulting in malignant transformation of …
expression often leads to cell cycle disorders, resulting in malignant transformation of …
MicroRNA involvement in signaling pathways during viral infection
MG Barbu, CE Condrat, DC Thompson… - Frontiers in cell and …, 2020 - frontiersin.org
The study of miRNAs started in 1993, when Lee et al. observed their involvement in the
downregulation of a crucial protein known as LIN-14 in the nematode Caenorhabditis …
downregulation of a crucial protein known as LIN-14 in the nematode Caenorhabditis …
[HTML][HTML] Translational genomics of nasopharyngeal cancer
Nasopharyngeal carcinoma (NPC), also named the Cantonese cancer, is a unique cancer
with strong etiological association with infection of the Epstein-Barr virus (EBV). With …
with strong etiological association with infection of the Epstein-Barr virus (EBV). With …
Epstein–Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating PTEN-dependent pathways in nasopharyngeal carcinoma
L Cai, Y Ye, Q Jiang, Y Chen, X Lyu, J Li… - Nature …, 2015 - nature.com
Abstract Epstein–Barr virus (EBV), aetiologically linked to nasopharyngeal carcinoma
(NPC), is the first human virus found to encode many miRNAs. However, how these viral …
(NPC), is the first human virus found to encode many miRNAs. However, how these viral …
EBV-miR-BART7-3p promotes the EMT and metastasis of nasopharyngeal carcinoma cells by suppressing the tumor suppressor PTEN
LM Cai, XM Lyu, WR Luo, XF Cui, YF Ye, CC Yuan… - Oncogene, 2015 - nature.com
The epithelial-mesenchymal transition (EMT) is crucial to cancer progression and
metastasis. Although multiple cellular miRNAs have been identified to regulate the EMT and …
metastasis. Although multiple cellular miRNAs have been identified to regulate the EMT and …
The role of microRNAs in the pathogenesis of herpesvirus infection
D Piedade, JM Azevedo-Pereira - Viruses, 2016 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs important in gene regulation. They are
able to regulate mRNA translation through base-pair complementarity. Cellular miRNAs …
able to regulate mRNA translation through base-pair complementarity. Cellular miRNAs …