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Light-triggered photodynamic nanomedicines for overcoming localized therapeutic efficacy in cancer treatment
Photodynamic nanomedicines have significantly enhanced the therapeutic efficacy of
photosensitizers (PSs) by overcoming critical limitations of PSs such as poor water solubility …
photosensitizers (PSs) by overcoming critical limitations of PSs such as poor water solubility …
Gel formulations for topical treatment of skin cancer: A review
Skin cancer, with all its variations, is the most common type of cancer worldwide.
Chemotherapy by topical application is an attractive strategy because of the ease of …
Chemotherapy by topical application is an attractive strategy because of the ease of …
Enzyme-responsive double-locked photodynamic molecular beacon for targeted photodynamic anticancer therapy
An advanced photodynamic molecular beacon (PMB) was designed and synthesized, in
which a distyryl boron dipyrromethene (DSBDP)-based photosensitizer and a Black Hole …
which a distyryl boron dipyrromethene (DSBDP)-based photosensitizer and a Black Hole …
Specific activation of photosensitizer with extrinsic enzyme for precisive photodynamic therapy
Delivery of functional proteins into the intracellular space has been a challenging task that
could lead to a myriad of therapeutic applications. We report herein a novel bioconjugation …
could lead to a myriad of therapeutic applications. We report herein a novel bioconjugation …
Trial watch: An update of clinical advances in photodynamic therapy and its immunoadjuvant properties for cancer treatment
M Penetra, LG Arnaut, LC Gomes-da-Silva - 2023 - Taylor & Francis
Photodynamic therapy (PDT) is a medical treatment used to target solid tumors, where the
administration of a photosensitizing agent and light generate reactive oxygen species …
administration of a photosensitizing agent and light generate reactive oxygen species …
Recent progress in multifunctional conjugated polymer nanomaterial-based synergistic combination phototherapy for microbial infection theranostics
Microbial infection is a critical public health problem, owing to its strong infectivity and high
risk of mortality. Multi-antibiotic resistant pathogens reduce the efficacy of commercial …
risk of mortality. Multi-antibiotic resistant pathogens reduce the efficacy of commercial …
[HTML][HTML] Aptamers as smart ligands for targeted drug delivery in cancer therapy
Z Wei, Y Zhou, R Wang, J Wang, Z Chen - Pharmaceutics, 2022 - mdpi.com
Undesirable side effects and multidrug tolerance are the main holdbacks to the treatment of
cancer in conventional chemotherapy. Fortunately, targeted drug delivery can improve the …
cancer in conventional chemotherapy. Fortunately, targeted drug delivery can improve the …
Toward precise antitumoral photodynamic therapy using a dual receptor‐mediated bioorthogonal activation approach
Targeted delivery and specific activation of photosensitizers can greatly improve the
treatment outcome of photodynamic therapy. To this end, we report herein a novel dual …
treatment outcome of photodynamic therapy. To this end, we report herein a novel dual …
Inducing Immunogenic Cancer Cell Death through Oxygen‐Economized Photodynamic Therapy with Nitric Oxide‐Releasing Photosensitizers
Photodynamic therapy (PDT) utilizes reactive oxygen species (ROS) for eradication of
cancer cells. Its effectiveness is governed by the oxygen content, which is scarce in the …
cancer cells. Its effectiveness is governed by the oxygen content, which is scarce in the …
Nanomedicines: Emerging platforms in smart chemotherapy treatment—a recent review
Cancer continues to pose one of the most critical challenges in global healthcare. Despite
the wide array of existing cancer drugs, the primary obstacle remains in selectively targeting …
the wide array of existing cancer drugs, the primary obstacle remains in selectively targeting …