Bipolar disorder (also known as manic depressive illness) is a complex genetic disorder in
which the core feature is pathological disturbance in mood (affect) ranging from extreme …

Although the involvement of genomic factors in bipolar disorder is evident, there are still
many unclear points about its pathophysiology. We proposed the mitochondrial dysfunction …

We performed a genome-wide association scan in 1461 patients with bipolar (BP) 1
disorder, 2008 controls drawn from the Systematic Treatment Enhancement Program for …

Identification of the genetic bases for bipolar disorder remains a challenge for the
understanding of this disease. Association between 76 candidate genes and bipolar …

Using genotypes from nearly 8,000 short tandem-repeat polymorphisms typed in eight of the
reference families from the Centre d'Étude du Polymorphisme Humain (CEPH), we identified …

A genome-wide association study was carried out in 1020 case subjects with recurrent early-
onset major depressive disorder (MDD)(onset before age 31) and 1636 control subjects …

▪ Abstract Human behavioral genetic research aimed at characterizing the existence and
nature of genetic and environmental influences on individual differences in cognitive ability …

Key substantive findings from quantitative and molecular genetic research are reviewed in
relation to affective disorder, schizophrenia, autism, hyperkinetic/attention deficit disorder …

Schizophrenic and bipolar disorders are similar in several epidemiologic respects, including
age at onset, lifetime risk, course of illness, worldwide distribution, risk for suicide, gender …

Bipolar disorder is a severe mental illness characterized by mood swings of elation and
depression. Family, twin, and adoption studies suggest a complex genetic etiology that may …