Amorphous solid dispersions (ASDs) can increase the oral bioavailability of poorly soluble
drugs. However, their use in drug development is comparably rare due to a lack of basic …

At present, the majority of APIs synthesized today remain challenging tasks for formulation
development. Many technologies are being utilized or explored for enhancing solubility …

Current study is focused to enhance the solubility of poorly soluble drug olanzapine (OLZ)
by nanogels drug delivery system, as improved solubility is one of the most important …

Apremilast, a BCS class IV drug, has minimal solubility in aqueous medium which results in
poor bioavailability. With an intention of enhancing the bioavailability, amorphous solid …

The use of mesoporous silica nanoparticles (MSNs) in the field of oral drug delivery has
recently attracted greater attention. However, there is still limited knowledge about how the …

The article describes the preparation and characterization of 3D-printed tablets with
bicalutamide obtained using two-material co-extrusion-based fused deposition modeling …

Understanding the processing boundaries to generate crystalline solid dispersions (CSDs)
containing metastable polymorphs remains an untapped challenge for the application of hot …

Nanocrystals hold great potential as parenteral delivery carrier systems for poorly water-
soluble drugs. Elucidation of the in vivo fate of parenteral nanocrystals is of …

Cancer treatment has improved over the past decades, but a major challenge lies in drug
formulation, specifically for oral administration. Most anticancer drugs have poor water …

The self-assembly phenomenon of amphiphiles has attracted particular attention in recent
years due to its wide range of applications. The formation of nanoassemblies able to …