Epigenetic regulation of the innate immune response to infection
Q Zhang, X Cao - Nature Reviews Immunology, 2019 - nature.com
Innate immune cells have complex signalling pathways for sensing pathogens and initiating
innate immune responses against infection. These pathways are tightly regulated at different …
innate immune responses against infection. These pathways are tightly regulated at different …
Epigenetic remodeling in innate immunity and inflammation
Q Zhang, X Cao - Annual review of immunology, 2021 - annualreviews.org
The innate immune response is a rapid response to pathogens or danger signals. It is
precisely activated not only to efficiently eliminate pathogens but also to avoid excessive …
precisely activated not only to efficiently eliminate pathogens but also to avoid excessive …
Histone acetyltransferase 1 is a succinyltransferase for histones and non‐histones and promotes tumorigenesis
G Yang, Y Yuan, H Yuan, J Wang, H Yun, Y Geng… - EMBO …, 2021 - embopress.org
Lysine succinylation (Ksucc) is an evolutionarily conserved and widespread post‐
translational modification. Histone acetyltransferase 1 (HAT1) is a type B histone …
translational modification. Histone acetyltransferase 1 (HAT1) is a type B histone …
Histone acetyltransferase 1 promotes gemcitabine resistance by regulating the PVT1/EZH2 complex in pancreatic cancer
Y Sun, D Ren, Y Zhou, J Shen, H Wu, X ** - Cell Death & Disease, 2021 - nature.com
The poor prognosis of pancreatic cancer is primarily due to the development of resistance to
therapies, including gemcitabine. The long noncoding RNA PVT1 (lncRNA PVT1) has been …
therapies, including gemcitabine. The long noncoding RNA PVT1 (lncRNA PVT1) has been …
Histone acetylation dynamics integrates metabolic activity to regulate plant response to stress
Histone lysine acetylation is an essential chromatin modification for epigenetic regulation of
gene expression during plant response to stress. On the other hand, enzymes involved in …
gene expression during plant response to stress. On the other hand, enzymes involved in …
Identification of a histone family gene signature for predicting the prognosis of cervical cancer patients
X Li, R Tian, H Gao, Y Yang, BRG Williams… - Scientific reports, 2017 - nature.com
Heterogeneity in terms of tumor characteristics, prognosis, and survival among cancer
patients is an unsolved issue. Here, we systematically analyzed the aberrant expression …
patients is an unsolved issue. Here, we systematically analyzed the aberrant expression …
Differential responses by human respiratory epithelial cell lines to respiratory syncytial virus reflect distinct patterns of infection control
P Hillyer, R Shepard, M Uehling, M Krenz… - Journal of …, 2018 - Am Soc Microbiol
Respiratory syncytial virus (RSV) infects small foci of respiratory epithelial cells via infected
droplets. Infection induces expression of type I and III interferons (IFNs) and proinflammatory …
droplets. Infection induces expression of type I and III interferons (IFNs) and proinflammatory …
Epigenetic regulation of inflammation: The metabolomics connection
S Rath, YM Hawsawi, F Alzahrani, MI Khan - Seminars in Cell & …, 2024 - Elsevier
Epigenetic factors are considered the regulator of complex machinery behind inflammatory
disorders and significantly contributed to the expression of inflammation-associated genes …
disorders and significantly contributed to the expression of inflammation-associated genes …
The role of Ca2+-signaling in the regulation of epigenetic mechanisms
A Hernández-Oliveras, A Zarain-Herzberg - Cell Calcium, 2024 - Elsevier
Epigenetic mechanisms regulate multiple cell functions like gene expression and chromatin
conformation and stability, and its misregulation could lead to several diseases including …
conformation and stability, and its misregulation could lead to several diseases including …
Fish antiviral tripartite motif (TRIM) proteins
Tripartite motif (TRIM) family or RBCC proteins comprises characteristic zinc‐binding
domains (a RING (R), a B‐box type 1 (B1) and a B‐box type 2 (B2)) and coiled‐coil (CC) …
domains (a RING (R), a B‐box type 1 (B1) and a B‐box type 2 (B2)) and coiled‐coil (CC) …