Many cells are able to orient themselves in a non-uniform environment by responding to
localized cues. This leads to a polarized cellular response, where the cell can either grow or …

Cell–cell fusion in sexually reproducing organisms is a mechanism to merge gamete
genomes and, in multicellular organisms, it is a strategy to sculpt organs, such as muscle …

Cells live in a chemical environment and are able to orient towards chemical cues.
Unicellular haploid fungal cells communicate by secreting pheromones to reproduce …

We investigated the impact of the deletions of genes from the final steps in the biosynthesis
of ergosterol (ERG6, ERG2, ERG3, ERG5, ERG4) on the physiological function of the …

Sterols and sphingolipids are considered mainly eukaryotic lipids even though both are
present in some prokaryotes, with sphingolipids being more widespread than sterols. Both …

Tolerance of yeast to acid stress is important for many industrial processes including organic
acid production. Therefore, elucidating the molecular basis of long term adaptation to acidic …

Fungal species are a very important source of many different enzymes, and the ability of
fungi to transform steroids has been used for several decades in the production of …

Yeast strains have been used extensively as robust microbial cell factories for the production
of bulk and fine chemicals, including biofuels (bioethanol), complex pharmaceuticals …

Ecdysteroids are the hormones regulating development, physiology and fertility in
arthropods, which synthesize them exclusively from dietary sterols. But how dietary sterol …

Higher energy collision dissociation (HCD) is a complementary fragmentation tool that has
recently become available on mass spectrometers of the LTQ Orbitrap family. We report on a …