Dectin-1 signaling update: new perspectives for trained immunity

P Mata-Martínez, M Bergón-Gutiérrez… - Frontiers in …, 2022 - frontiersin.org
The C-type lectin receptor Dectin-1 was originally described as the β-glucan receptor
expressed in myeloid cells, with crucial functions in antifungal responses. However, over …

Trained immunity: Target for prophylaxis and therapy

A Ziogas, M Bruno, R van der Meel, WJM Mulder… - Cell host & …, 2023 - cell.com
Trained immunity is a de facto memory for innate immune responses, leading to long-term
functional reprogramming of innate immune cells. In physiological conditions, trained …

Trained immunity-related vaccines: innate immune memory and heterologous protection against infections

A Ziogas, MG Netea - Trends in molecular medicine, 2022 - cell.com
The innate immune system is able to build memory-like features in response to certain
infections or vaccines, resulting in enhanced responsiveness upon (re) challenge with the …

[HTML][HTML] Highly attenuated poxvirus-based vaccines against emerging viral diseases

B Perdiguero, P Pérez, L Marcos-Villar… - Journal of molecular …, 2023 - Elsevier
Although one member of the poxvirus family, variola virus, has caused one of the most
devastating human infections worldwide, smallpox, the knowledge gained over the last 30 …

Intranasal administration of a single dose of MVA-based vaccine candidates against COVID-19 induced local and systemic immune responses and protects mice from …

P Pérez, D Astorgano, G Albericio, S Flores… - Frontiers in …, 2022 - frontiersin.org
Current coronavirus disease-19 (COVID-19) vaccines are administered by the intramuscular
route, but this vaccine administration failed to prevent severe acute respiratory syndrome …

Endotoxin tolerance and trained immunity: breaking down immunological memory barriers

E López-Collazo, C Del Fresno - Frontiers in Immunology, 2024 - frontiersin.org
For decades, innate immune cells were considered unsophisticated first responders, lacking
the adaptive memory of their T and B cell counterparts. However, mounting evidence …

[HTML][HTML] Viral infection and airway epithelial immunity in asthma

SR Kim - International journal of molecular sciences, 2022 - mdpi.com
Viral respiratory tract infections are associated with asthma development and exacerbation
in children and adults. In the course of immune responses to viruses, airway epithelial cells …

[PDF][PDF] CAPÍTULO X

CR Hernández, SCF Martínez… - … en Ciencias de la …, 2024 - biblioteca.ciencialatina.org
Background: A factor that leads to detachment from breastfeeding is the lack of training, so
interventions must be carried out to guarantee its correct management. Objective: To …

Candida albicans V132 induces trained immunity and enhances the responses triggered by the polybacterial vaccine MV140 for genitourinary tract infections

L Martín-Cruz, A Angelina, I Baydemir, Ö Bulut… - Frontiers in …, 2022 - frontiersin.org
Introduction Recurrent urinary tract infections (RUTIs) and recurrent vulvovaginal
candidiasis (RVVCs) represent major healthcare problems all over the world. Antibiotics and …

Preclinical immune efficacy against SARS-CoV-2 beta B. 1.351 variant by MVA-based vaccine candidates

P Perez, G Albericio, D Astorgano, S Flores… - Frontiers in …, 2023 - frontiersin.org
The constant appearance of new severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants of concern (VoCs) has jeopardized the protective capacity of approved …