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Biosystem‐inspired engineering of nanozymes for biomedical applications
Nanozymes with intrinsic enzyme‐mimicking activities have shown great potential to
become surrogates of natural enzymes in many fields by virtue of their advantages of high …
become surrogates of natural enzymes in many fields by virtue of their advantages of high …
Designing nanozymes for in vivo applications
Biocatalytic drugs, including natural and artificial enzymes that can accelerate biochemical
reactions, are promising tools to address redox imbalances, metabolic disorders and …
reactions, are promising tools to address redox imbalances, metabolic disorders and …
Dipeptide coacervates as artificial membraneless organelles for bioorthogonal catalysis
Artificial organelles can manipulate cellular functions and introduce non-biological
processes into cells. Coacervate droplets have emerged as a close analog of …
processes into cells. Coacervate droplets have emerged as a close analog of …
Bioorthogonal-activated in situ vaccine mediated by a COF-based catalytic platform for potent cancer immunotherapy
Personalized tumor vaccines have become a promising modality for cancer immunotherapy.
However, in situ personalized tumor vaccines generated from immunogenic cancer cell …
However, in situ personalized tumor vaccines generated from immunogenic cancer cell …
Bioorthogonal disruption of pyroptosis checkpoint for high-efficiency pyroptosis cancer therapy
Pyroptosis is an inflammatory form of programmed cell death that holds great promise in
cancer therapy. However, autophagy as the crucial pyroptosis checkpoint and the self …
cancer therapy. However, autophagy as the crucial pyroptosis checkpoint and the self …
Integrated cascade nanozyme catalyzes in vivo ROS scavenging for anti-inflammatory therapy
Here, an integrated cascade nanozyme with a formulation of Pt@ PCN222-Mn is developed
to eliminate excessive reactive oxygen species (ROS). This nanozyme mimics superoxide …
to eliminate excessive reactive oxygen species (ROS). This nanozyme mimics superoxide …
Nanozyme: new horizons for responsive biomedical applications
Nanozymes are nanomaterial-based artificial enzymes. By effectively mimicking catalytic
sites of natural enzymes or harboring multivalent elements for reactions, nanozyme systems …
sites of natural enzymes or harboring multivalent elements for reactions, nanozyme systems …
Supramolecular cancer nanotheranostics
Among the many challenges in medicine, the treatment and cure of cancer remains an
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …
outstanding goal given the complexity and diversity of the disease. Nanotheranostics, the …
Nanozymes: classification, catalytic mechanisms, activity regulation, and applications
Because of the high catalytic activities and substrate specificity, natural enzymes have been
widely used in industrial, medical, and biological fields, etc. Although promising, they often …
widely used in industrial, medical, and biological fields, etc. Although promising, they often …
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II)
Nanozymes are nanomaterials with enzyme-like characteristics (Chem. Soc. Rev., 2013, 42,
6060–6093). They have been developed to address the limitations of natural enzymes and …
6060–6093). They have been developed to address the limitations of natural enzymes and …