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Food allergy
Food allergies manifest in a variety of clinical conditions within the gastrointestinal tract, skin
and lungs, with the most dramatic and sometimes fatal manifestation being anaphylactic …
and lungs, with the most dramatic and sometimes fatal manifestation being anaphylactic …
Intestinal dendritic cells in health and gut inflammation
AJ Stagg - Frontiers in immunology, 2018 - frontiersin.org
Dendritic cells (DCs) mediate tolerance to food antigens, limit reactivity to the gut microbiota
and are required for optimal response to intestinal pathogens. Intestinal DCs are …
and are required for optimal response to intestinal pathogens. Intestinal DCs are …
Intestinal bacteria and the regulation of immune cell homeostasis
The human intestine is colonized by an estimated 100 trillion bacteria. Some of these
bacteria are essential for normal physiology, whereas others have been implicated in the …
bacteria are essential for normal physiology, whereas others have been implicated in the …
Toll-like receptors in inflammatory bowel diseases: a decade later
Differential alteration of Toll-like receptor (TLR) expression in inflammatory bowel disease
(IBD) was first described 10 years ago. Since then, studies from many groups have led to the …
(IBD) was first described 10 years ago. Since then, studies from many groups have led to the …
Intestinal macrophages and dendritic cells: what's the difference?
Mononuclear phagocytes (MPs) in the murine intestine, comprising dendritic cells (DCs) and
macrophages (Mϕs), perform disparate yet complementary immunological functions …
macrophages (Mϕs), perform disparate yet complementary immunological functions …
Intestinal CD103+ dendritic cells: master regulators of tolerance?
CD103+ dendritic cells (DCs) in the intestinal mucosa play a crucial role in tolerance to
commensal bacteria and food antigens. These cells originate in the lamina propria (LP) and …
commensal bacteria and food antigens. These cells originate in the lamina propria (LP) and …
Intestinal CD103− dendritic cells migrate in lymph and prime effector T cells
Intestinal dendritic cells (DCs) continuously migrate through lymphatics to mesenteric lymph
nodes where they initiate immunity or tolerance. Recent research has focused on …
nodes where they initiate immunity or tolerance. Recent research has focused on …
Regulatory T cells reinforce intestinal homeostasis
Regulatory T cells help maintain intestinal homeostasis by preventing inappropriate innate
and adaptive immune responses. CD4+ T cells that express Foxp3 and Tr1-like cells that …
and adaptive immune responses. CD4+ T cells that express Foxp3 and Tr1-like cells that …
Gastrointestinal and hepatic mechanisms limiting entry and dissemination of lipopolysaccharide into the systemic circulation
The human microbiota consists of 100 trillion microorganisms that provide important
metabolic and biological functions benefiting the host. However, the presence in host …
metabolic and biological functions benefiting the host. However, the presence in host …
The effects of TLR activation on T‐cell development and differentiation
Invading pathogens have unique molecular signatures that are recognized by Toll‐like
receptors (TLRs) resulting in either activation of antigen‐presenting cells (APCs) and/or …
receptors (TLRs) resulting in either activation of antigen‐presenting cells (APCs) and/or …