Background Surgical approaches to orbital apex lesions involve the medial and lateral
corridors. The transorbital neuroendoscopic (TONE) approach has been recently proposed …

Objective Examination of the current trends and future perspectives of the cell-based
therapies in neurosurgery. Methods A PubMed/MEDLINE-based systematic review has …

Background and Objectives: Trauma coagulopathy begins at the moment of trauma. This
study investigated whether coagulopathy upon arrival in the emergency room (ER) is …

Background and objectives: Anticoagulants are thought to increase the risks of traumatic
intracranial injury and poor clinical outcomes after blunt head trauma. The safety of using …

Background: Immune tolerance, immune escape, neoangiogenesis, phenotypic changes,
and glioma stem cells are all responsible for the resistance of malignant brain tumors to …

Background Schwannomas encompassing the superior parapharyngeal space are
challenging lesions because of the anatomical complexity of this region and the frequent …

Objectives To report the results of a retrospective series and a technical note about the
anterolateral approach for the treatment of the rotational occlusion syndrome (ROS) …

Background: Adoptive immunotherapies are among the pillars of ongoing biological
breakthroughs in neuro-oncology, as their potential applications are tremendously wide. The …

Background: Stem cells (SCs) represent a recent and attractive therapeutic option for neuro-
oncology, as well as for treating degenerative, ischemic and traumatic pathologies of the …

Background: Gene therapy is the most attractive therapeutic approach against high-grade
gliomas (HGGs). This is because of its theoretical capability to rework gene makeup in order …