Abstract Type 1 diabetes currently affects 20–40 million people worldwide. Insulin treatment
is standard, but a majority of patients still experience glycemic instability and associated …

Pig islets are an alternative source for islet transplantation to treat type 1 diabetes (T1D), but
reproducible curative potential in the pig-to-nonhuman primate (NHP) model has not been …

摘要β 细胞补充治疗, 包括同种异体胰腺与胰岛移植, 对于脆性1 型糖尿病患者来说可使其
HbA1c 水****常化, 但是供体短缺是个严重的问题. 为了克服这个问题, 异种移植是一种吸引人 …

At the time the first pancreas transplant was performed by Kelly and Lillehei in 1966, insulin
therapy for diabetes was generally available but administered in a form that is known today …

The porcine cornea may be a good solution for the shortage of human donor corneas
because its size and refractive properties are comparable to those of the human cornea …

Purpose.: To solve the shortage of donor corneas, a decellularizing method based on
hypertonic saline treatment was introduced, and a favorable outcome was observed in pig-to …

Graham ML, Bellin MD, Papas KK, Hering BJ, Schuurman H‐J. Species incompatibilities in
the pig‐to‐macaque islet xenotransplant model affect transplant outcome: a comparison with …

Abstract The International Xenotransplantation Association has updated its original
“Consensus Statement on Conditions for Undertaking Clinical Trials of Porcine Islet …

The potential use of allogeneic islet transplantation in curing type 1 diabetes mellitus has
been adequately demonstrated, but its large-scale application is limited by the short supply …

In preparation for islet transplantation, diabetes was induced using streptozotocin (STZ) in
non-human primates ranging from juveniles to adults with diverse body types: we studied …