Oxidative stress in depression: the link with the stress response, neuroinflammation, serotonin, neurogenesis and synaptic plasticity

AS Correia, A Cardoso, N Vale - Antioxidants, 2023 - mdpi.com
Depression is a prevalent, complex, and highly debilitating disease. The full comprehension
of this disease is still a global challenge. Indeed, relapse, recurrency, and therapeutic …

Fluid transport in the brain

MK Rasmussen, H Mestre… - Physiological …, 2022 - journals.physiology.org
The brain harbors a unique ability to, figuratively speaking, shift its gears. During
wakefulness, the brain is geared fully toward processing information and behaving, while …

Depresión, estrés y ansiedad en estudiantes de Medicina humana de Ayacucho (Perú) en el contexto de la pandemia por COVID-19

KD Sandoval, PV Morote-Jayacc… - Revista Colombiana de …, 2023 - Elsevier
Objetivo Evaluar la frecuencia de ansiedad, depresión y estrés, así como sus factores
asociados y los cambios de hábitos, en estudiantes de Medicina humana de la Universidad …

[HTML][HTML] Spatial epigenome–transcriptome co-profiling of mammalian tissues

D Zhang, Y Deng, P Kukanja, E Agirre, M Bartosovic… - Nature, 2023 - nature.com
Emerging spatial technologies, including spatial transcriptomics and spatial epigenomics,
are becoming powerful tools for profiling of cellular states in the tissue context,,,–. However …

[HTML][HTML] The prevalence and national burden of treatment-resistant depression and major depressive disorder in the United States

M Zhdanava, D Pilon, I Ghelerter… - The Journal of …, 2021 - legacy.psychiatrist.com
Objective: Estimates of prevalence and burden of treatment-resistant depression (TRD) vary
widely in the literature. This study evaluated the prevalence and burden of TRD and the …

The role of histone modifications: from neurodevelopment to neurodiseases

J Park, K Lee, K Kim, SJ Yi - Signal transduction and targeted therapy, 2022 - nature.com
Epigenetic regulatory mechanisms, including DNA methylation, histone modification,
chromatin remodeling, and microRNA expression, play critical roles in cell differentiation …

Comorbid depression in medical diseases

SM Gold, O Köhler-Forsberg, R Moss-Morris… - Nature Reviews …, 2020 - nature.com
Depression is one of the most common comorbidities of many chronic medical diseases
including cancer and cardiovascular, metabolic, inflammatory and neurological disorders …

Post-stroke depression: a 2020 updated review

GC Medeiros, D Roy, N Kontos, SR Beach - General hospital psychiatry, 2020 - Elsevier
Background Post-stroke depression (PSD) is common and associated with higher mortality,
poorer recovery, more pronounced cognitive deficits, and lower quality of life than is stroke …

Applications of focused ultrasound in the brain: from thermoablation to drug delivery

Y Meng, K Hynynen, N Lipsman - Nature Reviews Neurology, 2021 - nature.com
Focused ultrasound (FUS) is a disruptive medical technology, and its implementation in the
clinic represents the culmination of decades of research. Lying at the convergence of …

A Delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials

L Sforzini, C Worrell, M Kose, IM Anderson… - Molecular …, 2022 - nature.com
Criteria for treatment-resistant depression (TRD) and partially responsive depression (PRD)
as subtypes of major depressive disorder (MDD) are not unequivocally defined. In the …