Targeted therapy for head and neck cancer: signaling pathways and clinical studies
Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …
Immunotherapy and biomarker testing in recurrent and metastatic head and neck cancers: ASCO guideline
PURPOSE To provide evidence-based recommendations for practicing physicians and
other health care providers on immunotherapy and biomarker testing for head and neck …
other health care providers on immunotherapy and biomarker testing for head and neck …
Camrelizumab combined with apatinib in patients with first-line platinum-resistant or PD-1 inhibitor resistant recurrent/metastatic nasopharyngeal carcinoma: a single …
L Yuan, GD Jia, XF Lv, SY **e, SS Guo, DF Lin… - Nature …, 2023 - nature.com
Immunotherapy combined with antiangiogenic targeted therapy has improved the treatment
of certain solid tumors, but effective regimens remain elusive for refractory …
of certain solid tumors, but effective regimens remain elusive for refractory …
Analytical validation of NavDx, a cfDNA-based fragmentomic profiling assay for HPV-driven cancers
A Gunning, S Kumar, CK Williams, BM Berger… - Diagnostics, 2023 - mdpi.com
The NavDx® blood test analyzes tumor tissue modified viral (TTMV)-HPV DNA to provide a
reliable means of detecting and monitoring HPV-driven cancers. The test has been clinically …
reliable means of detecting and monitoring HPV-driven cancers. The test has been clinically …
Current perspectives on recurrent HPV-mediated oropharyngeal cancer
In the recent years, the prevalence of HPV-positive oropharyngeal squamous cell carcinoma
(OPSCC) has increased significantly. Currently, nearly 80-90% of all oropharynx tumors are …
(OPSCC) has increased significantly. Currently, nearly 80-90% of all oropharynx tumors are …
Combination therapy as a promising way to fight oral cancer
Oral cancer is a highly aggressive tumor with invasive properties that can lead to metastasis
and high mortality rates. Conventional treatment strategies, such as surgery, chemotherapy …
and high mortality rates. Conventional treatment strategies, such as surgery, chemotherapy …
Circulating tumor HPV DNA for surveillance of HPV-positive oropharyngeal squamous cell carcinoma: A narrative review
Importance Human papillomavirus (HPV)–positive oropharyngeal squamous cell carcinoma
has an overall favorable prognosis, yet a subset of patients will experience devastating …
has an overall favorable prognosis, yet a subset of patients will experience devastating …
Characterization of immune microenvironment in patients with HPV-positive and negative head and neck cancer
Z Wang, Q Wang, Y Tao, J Chen, Z Yuan, P Wang - Scientific Data, 2023 - nature.com
Human papillomavirus (HPV) status strongly predicts positive clinical outcomes in patients
with head and neck squamous cell cancer (HNSCC); however, the potential reasons have …
with head and neck squamous cell cancer (HNSCC); however, the potential reasons have …
Less is more: Exploring neoadjuvant immunotherapy as a de-escalation strategy in head and neck squamous cell carcinoma treatment
LM Cao, NN Zhong, Y Chen, ZZ Li, GR Wang, Y **ao… - Cancer Letters, 2024 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) constitutes a significant global cancer
burden, given its high prevalence and associated mortality. Despite substantial progress in …
burden, given its high prevalence and associated mortality. Despite substantial progress in …
Cinnamomum zeylanicum Extract and its Bioactive Component Cinnamaldehyde Show Anti-Tumor Effects via Inhibition of Multiple Cellular Pathways
S Aggarwal, K Bhadana, B Singh, M Rawat… - Frontiers in …, 2022 - frontiersin.org
Cinnamomum zeylanicum is a tropical plant with traditional medicinal significance that
possesses antimicrobial, antifungal, anti-parasitic, and anti-tumor properties. Here, we have …
possesses antimicrobial, antifungal, anti-parasitic, and anti-tumor properties. Here, we have …