Cancer of unknown primary (CUP) origin is an enigmatic group of diagnoses in which the
primary anatomical site of tumour origin cannot be determined,. This poses a considerable …

Cancer of unknown primary (CUP) is an enigmatic disease entity encompassing
heterogeneous malignancies without a detectable primary tumour, despite a thorough …

Cancer of unknown primary (CUP) affects a small percentage of the general population.
Nonetheless, a substantial number of these patients have a poor prognosis and …

Background Patients with unfavourable subset cancer of unknown primary (CUP) have a
poor prognosis when treated with standard platinum-based chemotherapy. Whether first-line …

Cancer of unknown primary (CUP) site poses diagnostic challenges due to its elusive
nature. Many cases of CUP manifest as pleural and peritoneal serous effusions. Leveraging …

Abstract Cancers of Unknown Primary Site (CUP) account for approximately 1–3% of all
malignant neoplasms. It represents a heterogeneous group of malignancies without a …

Cancer of unknown primary (CUP) is a syndrome defined by clinical absence of a primary
cancer after standardised investigations. Gene expression profiling (GEP) and DNA …

Simple Summary Patients with cancer of unknown primary site suffer the burden of an
uncertain disease, which is characterized by the impossibility to identify the tissue where the …

Background Although the incidence of Cancer of Unknown Primary (CUP) is estimated to be
1–2% of all cancers worldwide, no international standards for diagnostic workup are yet …

Background Cancer of unknown primary site (CUP) is a term applied to characterize
pathologically confirmed metastatic cancer with unknown primary tumor origin. It remains …