Endocytic recycling
After endocytosis, most membrane proteins and lipids return to the cell surface, but some
membrane components are delivered to late endosomes or the Golgi. We now understand …
membrane components are delivered to late endosomes or the Golgi. We now understand …
Sorting out the cellular functions of sorting nexins
CA Worby, JE Dixon - Nature reviews Molecular cell biology, 2002 - nature.com
Sorting nexins are a diverse group of cellular trafficking proteins that are unified by the
presence of a phospholipid-binding motif—the PX domain. The ability of these proteins to …
presence of a phospholipid-binding motif—the PX domain. The ability of these proteins to …
Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5, and Rab11
Two endosome populations involved in recycling of membranes and receptors to the plasma
membrane have been described, the early and the recycling endosome. However, this …
membrane have been described, the early and the recycling endosome. However, this …
Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform
F Mallard, BL Tang, T Galli, D Tenza… - The Journal of cell …, 2002 - rupress.org
The molecular mechanisms underlying early/recycling endosomes-to-TGN transport are still
not understood. We identified interactions between the TGN-localized putative t-SNAREs …
not understood. We identified interactions between the TGN-localized putative t-SNAREs …
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer β-amyloid peptides
The excessive generation and accumulation of 40-and 42-aa β-amyloid peptides
(Aβ40/Aβ42) in selectively vulnerable brain regions is a major neuropathological feature of …
(Aβ40/Aβ42) in selectively vulnerable brain regions is a major neuropathological feature of …
[HTML][HTML] Tracing the retrograde route in protein trafficking
L Johannes, V Popoff - Cell, 2008 - cell.com
Retrograde transport, in which proteins and lipids are shuttled between endosomes and
biosynthetic/secretory compartments such as the Golgi apparatus, is crucial for a diverse …
biosynthetic/secretory compartments such as the Golgi apparatus, is crucial for a diverse …
Electron Tomography of RabA4b‐ and PI‐4Kβ1‐Labeled Trans Golgi Network Compartments in Arabidopsis
The trans Golgi network (TGN) of plant cells sorts and packages Golgi products into
secretory (SV) and clathrin‐coated (CCV) vesicles. We have analyzed of TGN cisternae in …
secretory (SV) and clathrin‐coated (CCV) vesicles. We have analyzed of TGN cisternae in …
Rab GTPases coordinate endocytosis
JS Rodman, A Wandinger-Ness - Journal of cell science, 2000 - journals.biologists.com
Endocytosis is characterized by vesicular transport along numerous pathways. Common
steps in each pathway include membrane budding to form vesicles, transport to a particular …
steps in each pathway include membrane budding to form vesicles, transport to a particular …
Lipids as targeting signals: lipid rafts and intracellular trafficking
JB Helms, C Zurzolo - Traffic, 2004 - Wiley Online Library
Our view of biological membranes has evolved dramatically over the last few decades. In the
bilayer model from Singer & Nicholson (Science 1972; 175: 720–731), both proteins and …
bilayer model from Singer & Nicholson (Science 1972; 175: 720–731), both proteins and …
An NMDA receptor ER retention signal regulated by phosphorylation and alternative splicing
Formation of mature excitatory synapses requires the assembly and delivery of NMDA
receptors to the neuronal plasma membrane. A key step in the trafficking of NMDA receptors …
receptors to the neuronal plasma membrane. A key step in the trafficking of NMDA receptors …