Poor water solubility, off-target toxicity, and small therapeutic window are among major
obstacles for the development of drug products. Redox-responsive drug delivery …

The pioneering work on liposomes in the 1960s and subsequent research in controlled drug
release systems significantly advances the development of nanocarriers (NCs) for drug …

In this review, we have focused on the design and development of low molecular weight self-
assembling peptide-based materials for various applications including cell proliferation …

To mimic proteins, artificial designed self-assembling peptides (SAPs) that form diverse
ordered nanostructures have been developed and served in biomedicine fields. In this …

Conspectus Spherical ordering from small molecules is a subject of intense interest to
chemists. The inherent capability of amphiphiles to assemble spontaneously is the unique …

Targeted delivery of hydrophobic chemotherapeutic drugs to tumor cells remains a
fundamental problem in cancer therapy. Effective encapsulation of hydrophobic drugs in …

In this paper, we present well-defined dPGS-SS-PCL/PLGA/PLA micellar systems
demonstrating excellent capabilities as a drug delivery platform in light of high stability and …

Significance: Redox and epigenetics are two important regulatory processes of cell
physiological functions. The cross-regulation between these processes has critical effects on …

Chemists are increasingly turning to biology for inspiration to develop novel and superior
synthetic materials. Here, we present an innovative peptide design strategy for tubular …

Tryptophan as an aromatic amino acid with a hydrophobic indole group plays important
roles in stabilizing protein structures and enhancing molecular bindings in nature, but was …