Streptococcus pyogenes adhesion and colonization

S Brouwer, TC Barnett, T Rivera‐Hernandez… - FEBS …, 2016 - Wiley Online Library
Streptococcus pyogenes (group A Streptococcus, GAS) is a human‐adapted pathogen
responsible for a wide spectrum of disease. GAS can cause relatively mild illnesses, such as …

Collagen‐like proteins of pathogenic streptococci

S Lukomski, BA Bachert, F Squeglia… - Molecular …, 2017 - Wiley Online Library
The collagen domain, which is defined by the presence of the Gly‐X‐Y triplet repeats, is
amongst the most versatile and widespread known structures found in proteins from …

Bacterial collagen-like proteins that form triple-helical structures

Z Yu, B An, JAM Ramshaw, B Brodsky - Journal of structural biology, 2014 - Elsevier
A large number of collagen-like proteins have been identified in bacteria during the past 10
years, principally from analysis of genome databases. These bacterial collagens share the …

Apolipoprotein B is an innate barrier against invasive Staphylococcus aureus infection

MM Peterson, JL Mack, PR Hall, AA Alsup… - Cell host & …, 2008 - cell.com
Staphylococcus aureus is both a colonizer of humans and a cause of severe invasive
infections. Although the genetic basis for phenotype switching from colonizing to invasive …

Self-Assembling Triple-Helix Recombinant Collagen Hydrogel Enriched with Tyrosine

H He, N Wei, Y **e, L Wang, L Yao… - … Biomaterials Science & …, 2024 - ACS Publications
The self-assembly of collagen within the human body creates a complex 3D fibrous network,
providing structural integrity and mechanical strength to connective tissues. Recombinant …

Bioactive hydrogels based on designer collagens

E Cosgriff-Hernandez, MS Hahn, B Russell, T Wilems… - Acta biomaterialia, 2010 - Elsevier
Designer Collagens are based on streptococcal collagen-like (Scl) proteins that form a triple
helix similar to mammalian collagens but that are non-platelet aggregating. In contrast to the …

Plasma lipoproteins are important components of the immune system

R Han - Microbiology and immunology, 2010 - Wiley Online Library
ABSTRACT Plasma lipoproteins (VLDL, LDL, Lp [a] and HDL) function primarily in lipid
transport among tissues and organs. However, cumulative evidence suggests that …

An engineered α1 integrin-binding collagenous sequence

N Seo, BH Russell, JJ Rivera, X Liang, X Xu… - Journal of Biological …, 2010 - jbc.org
Collagen is an extracellular matrix structural component that can regulate cellular processes
through its interaction with the integrins, α1β1, α2β1, α10β1, and α11β1. Collagen-like …

Scl1, the multifunctional adhesin of group A Streptococcus, selectively binds cellular fibronectin and laminin, and mediates pathogen internalization by human cells

CC Caswell, H Oliver-Kozup, R Han… - FEMS microbiology …, 2010 - academic.oup.com
The streptococcal collagen-like protein-1, Scl1, is widely expressed by the well-recognized
human pathogen group A Streptococcus (GAS). Screening of human ligands for binding to …

Spatio-temporal modification of collagen scaffolds mediated by triple helical propensity

AY Wang, CA Foss, S Leong, X Mo… - …, 2008 - ACS Publications
Functionalized collagen that incorporates exogenous compounds may offer new and
improved biomaterials applications, especially in drug-delivery, multifunctional implants, and …