Over the past two decades, significant progress in understanding of the pathogenesis of type
2 chronic inflammatory diseases has enabled the identification of compounds for more than …

Urticaria is a condition characterized by the development of itchy wheals (hives),
angioedema, or both. The pathophysiology of chronic spontaneous urticaria (CSU) is still …

Basophils are rare cells in the peripheral blood which have the capability to infiltrate into the
skin. Invasion of basophils has been detected in pruritic skin diseases, including atopic …

Background The growing consensus links exposure to fine particulate matter (PM 2.5) with
an increased risk of respiratory diseases. However, little is known about the additional …

Atopic dermatitis (AD) is the most common chronic relapsing neuroinflammatory skin
disease that is characterized by a complex and multifactorial pathophysiology. It reflects a …

Background Endoscopic vidian neurectomy is expected to provide good therapeutic relief in
patients with allergic rhinitis (AR) being refractory to medication therapy or conservative …

The prevalence rate of allergic rhinitis (AR) is high worldwide. The inhalation of allergens
induces AR, which is an immunoglobulin E-mediated and type 2 inflammation-driven …

Background Anxiety about using topical corticosteroids (TCS) for childrens among parents
and caretakers is a common cause of treatment failure and an overall decline in the child's …

Atopic dermatitis (AD) is a recurrent, chronic, inflammatory, itchy skin disorder that affects up
to 20% of the pediatric population and 10% of the adult population worldwide. Onset …

Background Chronic urticaria (CU) has been shown to impact patients' quality of life
negatively and may coexist with psychiatric disorders. We systematically reviewed the …