Biomolecular damage induced by ionizing radiation: the direct and indirect effects of low-energy electrons on DNA

E Alizadeh, TM Orlando, L Sanche - Annual review of physical …, 2015 - annualreviews.org
Many experimental and theoretical advances have recently allowed the study of direct and
indirect effects of low-energy electrons (LEEs) on DNA damage. In an effort to explain how …

Electron-induced damage of DNA and its components: Experiments and theoretical models

I Baccarelli, I Bald, FA Gianturco, E Illenberger… - Physics Reports, 2011 - Elsevier
It is now over ten years since the seminal experiments of Leon Sanche's group in
Sherbrooke have compellingly shown that subexcitation electrons interacting with DNA …

Low energy electron-driven damage in biomolecules

L Sanche - The European Physical Journal D-Atomic, Molecular …, 2005 - Springer
The damage induced by the impact of low energy electrons (LEE) on biomolecules is
reviewed from a radiobiological perspective with emphasis on transient anion formation. The …

Molecular anions

J Simons - The Journal of Physical Chemistry A, 2008 - ACS Publications
The experimental and theoretical study of molecular anions has undergone explosive
growth over the past 40 years. Advances in techniques used to generate anions in …

How do low-energy (0.1− 2 eV) electrons cause DNA-strand breaks?

J Simons - Accounts of chemical research, 2006 - ACS Publications
We overview our recent theoretical predictions and the innovative experimental findings that
inspired us concerning the mechanisms by which very low-energy (0.1− 2 eV) free electrons …

Recent progress in dissociative electron attachment: from diatomics to biomolecules

II Fabrikant, S Eden, NJ Mason, J Fedor - Advances in atomic, molecular …, 2017 - Elsevier
Dissociative electron attachment (DEA) processes occur in many important applied contexts,
particularly gas discharges, plasmas, biological systems, and astrophysical environments. In …

Interactions of electrons with bare and hydrated biomolecules: From nucleic acid bases to DNA segments

J Gu, J Leszczynski, HF Schaefer III - Chemical reviews, 2012 - ACS Publications
The broadest motivation for exploring electron attachment to biological molecules comes
from their important role in radiation damage. Large quantities of secondary electrons with …

Mechanisms of nanoparticle radiosensitization

I Kempson - Wiley Interdisciplinary Reviews: Nanomedicine …, 2021 - Wiley Online Library
Metal‐based nanoparticles applied to potentiating the effects of radiotherapy have drawn
significant attention from the research community and are now available clinically. By …

Bond breaks of nucleotides by dissociative electron transfer of nonequilibrium prehydrated electrons: a new molecular mechanism for reductive DNA damage

CR Wang, J Nguyen, QB Lu - Journal of the American Chemical …, 2009 - ACS Publications
DNA damage is a central mechanism in the pathogenesis and treatment of human diseases,
notably cancer. Little is known about reductive DNA damage in causing genetic mutations …

Dissociative electron attachment to DNA

X Pan, P Cloutier, D Hunting, L Sanche - Physical review letters, 2003 - APS
Electron-stimulated desorption of anions from thin films of linear and supercoiled DNA is
investigated in the range 3–20 eV. Resonant structures are observed with maxima at …