Immune-microbe interactions early in life: A determinant of health and disease long term

P Brodin - Science, 2022 - science.org
Research on newborn immunity has revealed the importance of cell ontogeny, feto-maternal
tolerance, and the transfer of maternal antibodies. Less is known about postnatal adaptation …

The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract

O Perdijk, R Azzoni, BJ Marsland - Physiological Reviews, 2024 - journals.physiology.org
The last decade of microbiome research has highlighted its fundamental role in systemic
immune and metabolic homeostasis. The microbiome plays a prominent role during …

Maternal-infant antibiotic resistance genes transference: what do we know?

A Samarra, M Esteban-Torres, R Cabrera-Rubio… - Gut …, 2023 - Taylor & Francis
Resistance to antibiotics is becoming a worldwide threat as infections caused by multidrug-
resistant pathogenic microorganisms can overcome antibiotic treatments and spread quickly …

The resistance within: antibiotic disruption of the gut microbiome and resistome dynamics in infancy

R Thänert, SS Sawhney, DJ Schwartz, G Dantas - Cell host & microbe, 2022 - cell.com
Intestinal host-microbiota interactions during the first year of life are critical for infant
development. Early-life antibiotic exposures disrupt stereotypical gut microbiota maturation …

Pregnancy health in a multi-state US population of systemically underserved patients and their children: PROMISE cohort design and baseline characteristics

J Boone-Heinonen, K Lyon-Scott, R Springer… - BMC public health, 2024 - Springer
Background Gestational weight gain (GWG) is a routinely monitored aspect of pregnancy
health, yet critical gaps remain about optimal GWG in pregnant people from socially …

Cleaning of anthropometric data from PCORnet electronic health records using automated algorithms

PID Lin, SL Rifas-Shiman, IM Aris, MF Daley… - JAMIA …, 2022 - academic.oup.com
Objective To demonstrate the utility of growthcleanr, an anthropometric data cleaning
method designed for electronic health records (EHR). Materials and Methods We used all …

Synergistic horizontal transfer of antibiotic resistance genes and transposons in the infant gut microbial genome

Y Ding, X Jiang, J Wu, Y Wang, L Zhao, Y Pan, Y **… - Msphere, 2024 - journals.asm.org
Transposons, plasmids, bacteriophages, and other mobile genetic elements facilitate
horizontal gene transfer in the gut microbiota, allowing some pathogenic bacteria to acquire …

[HTML][HTML] Association of neonatal antibiotic exposure with long-term growth trajectory faltering in preterm-birth children

YC Lin, CH Chu, YK Lin, CC Chen, LW Chen… - Neonatology, 2024 - karger.com
Introduction: Preterm neonates often receive a variety of duration of antibiotic exposure
during admission. The aim of the study was to evaluate whether neonatal antibiotic …

Temporal development and potential interactions between the gut microbiome and resistome in early childhood

L Zhao, X Yang, Y Liang, Z Zhang, Y Ding… - Microbiology …, 2024 - journals.asm.org
Antimicrobial resistance-associated infections have become a major threat to global health.
The gut microbiome serves as a major reservoir of bacteria with antibiotic resistance genes; …

Prenatal and Early‐Life Anti‐Infectives and Obesity at Age 7 Years

SB Gribsholt, SK Szépligeti… - … and Drug Safety, 2024 - Wiley Online Library
Purpose To examine associations of prenatal and early‐life anti‐infective exposures with
obesity at 7 years. Methods In this nationwide, registry‐based, prevalence study, we …