Bile acids (BAs) are amphipathic steroid acids whose production and diversity depend on
both host and microbial metabolism. These metabolites have emerged as biologically active …

In 1995, the nuclear hormone orphan receptor farnesoid X receptor (FXR, NR1H4) was
identified as a farnesol receptor expressed mainly in liver, kidney, and adrenal gland of rats …

Bile acids facilitate nutrient absorption and are endogenous ligands for nuclear receptors
that regulate lipid and energy metabolism. The brain–gut–liver axis plays an essential role in …

Bile acid synthesis is the most significant pathway for catabolism of cholesterol and for
maintenance of whole body cholesterol homeostasis. Bile acids are physiological …

Obesity is a highly prevalent public health concern, attributed to multifactorial causes and
limited in treatment options. Several comorbidities are closely associated with obesity such …

OBJECTIVE To determine whether silastic ring laparoscopic Roux-en-Y gastric bypass (SR-
LRYGB) or laparoscopic sleeve gastrectomy (LSG) produces superior diabetes remission at …

Objective: The aim of this study was to compare weight loss, obesity-related comorbidities,
and biochemical outcomes of LSG versus LRYGB through a meta-analysis of randomized …

Bariatric surgery is an effective treatment option for patients with type 2 diabetes mellitus
(T2DM) and obesity. This study aims to compare the effects of Roux‐en‐Y gastric bypass …

Diabetes and obesity have reached an epidemic status worldwide. Diabetes increases the
risk for cardiovascular disease and nonalcoholic fatty liver disease. Primary bile acids are …

Bariatric surgery is an effective intervention for management of obesity through treating
dysregulated appetite and achieving long-term weight loss maintenance. Moreover …