Submucosal glands contribute to airway surface liquid (ASL), a film that protects all airway
surfaces. Glandular mucus comprises electrolytes, water, the gel-forming mucin MUC5B …

Mucociliary clearance (MCC), the process in which airway mucus together with substances
trapped within are moved out of the lungs, is an important defence mechanism of the human …

The parasympathetic control of goblet cell secretion and the membrane events
accompanying accelerated mucus release were studied in large intestinal mucosal biopsies …

Allergic pulmonary reactions in vivo lead to airway constriction and mucous secretion,
whereas in vitro lung anaphylaxis leads to mediator release and increased mucous …

The anticholinergic, antimuscarinic compounds are potent and hitherto neglected
bronchodilators. Although atropine itself has drawbacks, principally related to its rapid …

β 2-Adrenergic agonists are commonly used asbronchodilators to treat patients with COPD.
In addition to prolongedbronchodilation, long-acting β 2-agonists (LABAs) exertother effects …

Nasal transepithelial electrical potential difference (PD) was estimated in vivo in normal
human subjects. The PD between a bridge perfused with Ringer's solution placed on the …

Mucus secretion and mucociliary transport are essential defense mechanisms of the
airways. Deviations in mucus composition and secretion can impede mucociliary transport …

Erythromycin and other antibiotics hlMl been uHd emplrlcslly In the treatment of patlenta with
chronic obstructive pUlmonary dl.....(CaPO). Westudied whsther this emplrlcsl role of …

Recent evidence demonstrates that the conditioning of inspired air is not confined to the
upper airways as formerly thought but rather involves as much of the tracheobronchial tree …