Polyploidy is a key mechanism of genome evolution and speciation, particularly in plants.
Many aspects of polyploidy have been elucidated with the tools that have become available …

Ribosome biogenesis is a crucial process for growth and constitutes the major consumer of
cellular resources. This pathway is subjected to very stringent regulation to ensure correct …

During the past two decades, there has been an explosion of new knowledge and
techniques in the field of recombinant protein expression. However, over-expression of …

Cell size varies during the cell cycle and in response to external stimuli. This requires the
tight coordination, or" scaling," of mRNA and protein quantities with the cell volume in order …

Metabolic modeling and machine learning are key components in the emerging next
generation of systems and synthetic biology tools, targeting the genotype–phenotype …

RNA-binding proteins like human antigen R (HuR) are key regulators in post-transcriptional
control of gene expression in several pathophysiological conditions. Diabetes adversely …

To maintain protein homeostasis in changing nutrient environments, cells must precisely
control the amount of their proteins, despite the accompanying changes in cell growth and …

Yeasts are widely used cell factories for commercial heterologous protein production,
however, specific productivities are usually tightly coupled to biomass formation. This greatly …

Growth of a cell and its subsequent division into daughters is a fundamental aspect of all
cellular living systems. During these processes, how do individual cells correct size …

It has become increasingly clear in the last few years that gene expression in eukaryotes is
not a linear process from mRNA synthesis in the nucleus to translation and degradation in …