Acute and chronic lung injuries are among the leading causes of mortality worldwide. Lung
injury can affect several components of the respiratory system, including the airways …

Trauma can affect any individual at any location and at any time over a lifespan. The
disruption of macrobarriers and microbarriers induces instant activation of innate immunity …

Background Treatment with bone-marrow-derived mesenchymal stromal cells (MSCs) has
shown benefits in preclinical models of acute respiratory distress syndrome (ARDS). Safety …

Rationale: We previously identified two acute respiratory distress syndrome (ARDS)
subphenotypes in two separate randomized controlled trials with differential response to …

Background Bronchopulmonary dysplasia (BPD) is the result of a complex process in which
several prenatal and/or postnatal factors interfere with lower respiratory tract development …

The monolayer of endothelial cells lining the vessel wall forms a semipermeable barrier (in
all tissue except the relatively impermeable blood–brain and inner retinal barriers) that …

The acute respiratory distress syndrome (ARDS) is an important cause of acute respiratory
failure that is often associated with multiple organ failure. Several clinical disorders can …

Alveolar epithelial–capillary barrier disruption is a hallmark of acute respiratory distress
syndrome (ARDS). Contribution of mitochondrial dysfunction to the compromised alveolar …

Emerging evidence suggests that extracellular vesicle (EV)–containing miRNAs mediate
intercellular communications in response to noxious stimuli. It remains unclear how a cell …

The acute respiratory distress syndrome (ARDS) causes 40% mortality in approximately
200,000 critically ill patients annually in the United States. ARDS is caused by protein-rich …