Polymeric hydrogels are fascinating platforms as 3D scaffolds for tissue repair and delivery
systems of therapeutic molecules and cells. Among others, methacrylated gelatin (GelMA) …

Peripheral nerve injuries (PNI) can have several etiologies, such as trauma and iatrogenic
interventions, that can lead to the loss of structure and/or function impairment. These …

The treatment of peripheral nerve defects has always been one of the most challenging
clinical practices in neurosurgery. Currently, nerve autograft is the preferred treatment …

Graft-host mechanical mismatch has been a longstanding issue in clinical applications of
synthetic scaffolds for soft tissue regeneration. Although numerous efforts have been …

Tissue engineering is an important field of regenerative medicine, which combines scaffolds
and cell transplantation to develop substitute tissues and/or promote tissue regeneration …

Functional polymeric micro-/nanofibers have emerged as promising materials for the
construction of structures potentially useful in biomedical fields. Among all kinds of …

Most tissues of the human body are characterized by highly anisotropic physical properties
and biological organization. Hydrogels have been proposed as scaffolding materials to …

Nerve guidance conduits (NGCs) have become a promising alternative for peripheral nerve
regeneration; however, the outcome of nerve regeneration and functional recovery is greatly …

Peripheral nerve injury is a challenging orthopedic condition that can be treated by autograft
transplantation, a gold standard treatment in the current clinical setting. Nevertheless, limited …

Unlike the central nervous system, the peripheral nervous system (PNS) has an inherent
capacity to regenerate following injury. However, in the case of large nerve defects where …