Precision diagnostics: moving towards protein biomarker signatures of clinical utility in cancer
CAK Borrebaeck - Nature Reviews Cancer, 2017 - nature.com
Interest in precision diagnostics has been fuelled by the concept that early detection of
cancer would benefit patients; that is, if detected early, more tumours should be resectable …
cancer would benefit patients; that is, if detected early, more tumours should be resectable …
Multifactorial scores and biomarkers of prognosis of acute pancreatitis: applications to research and practice
Acute pancreatitis (AP) is a severe inflammation of the pancreas presented with sudden
onset and severe abdominal pain with a high morbidity and mortality rate, if accompanied by …
onset and severe abdominal pain with a high morbidity and mortality rate, if accompanied by …
Serum biomarker signature-based liquid biopsy for diagnosis of early-stage pancreatic cancer
LD Mellby, AP Nyberg, JS Johansen… - Journal of Clinical …, 2018 - ascopubs.org
Purpose Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis, with a 5-year
survival of< 10% because of diffuse symptoms leading to late-stage diagnosis. That survival …
survival of< 10% because of diffuse symptoms leading to late-stage diagnosis. That survival …
Protein microarray technology: how far off is routine diagnostics?
The nature of protein microarray platforms is favorable for multiplexing, leading to the
development of tools for personalised medicine and highly precise diagnostics. However, to …
development of tools for personalised medicine and highly precise diagnostics. However, to …
Biomarkers of chronic pancreatitis: a systematic literature review
Background Chronic pancreatitis (CP) does not have diagnostic or prognostic biomarkers.
CP is the end stage of a progressive inflammatory syndrome that is diagnosed at late stages …
CP is the end stage of a progressive inflammatory syndrome that is diagnosed at late stages …
[HTML][HTML] Differential miRNA and protein expression reveals miR-1285, its targets TGM2 and CDH-1, as well as CD166 and S100A13 as potential new biomarkers in …
T Kolokotronis, B Majchrzak-Stiller, M Buchholz… - Cancers, 2024 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma is a very lethal tumor entity with the late
appearance of clinical signs and the absence of biomarkers for early diagnosis. Diabetes …
appearance of clinical signs and the absence of biomarkers for early diagnosis. Diabetes …
Proteomic and metaproteomic approaches to understand host–microbe interactions
The human body is composed not only of human cells but is occupied by bacteria, archaea,
fungi, and viruses; this ensemble of organisms (microbiota) and their expressed genes are …
fungi, and viruses; this ensemble of organisms (microbiota) and their expressed genes are …
A cost-effective high-throughput plasma and serum proteomics workflow enables map** of the molecular impact of total pancreatectomy with islet …
Blood is an ideal body fluid for the discovery or monitoring of diagnostic and prognostic
protein biomarkers. However, discovering robust biomarkers requires the analysis of large …
protein biomarkers. However, discovering robust biomarkers requires the analysis of large …
The role of proteomics in acute pancreatitis: new and old knowledge
P Ge, Y Luo, G Zhang, H Chen - Expert Review of Proteomics, 2024 - Taylor & Francis
Introduction Around 20% of individuals diagnosed with acute pancreatitis (AP) may develop
severe acute pancreatitis (SAP), possibly resulting in a mortality rate ranging from 15% to …
severe acute pancreatitis (SAP), possibly resulting in a mortality rate ranging from 15% to …
Immunocapture strategies in translational proteomics
Aiming at clinical studies of human diseases, antibody-assisted assays have been applied
to biomarker discovery and toward a streamlined translation from patient profiling to assays …
to biomarker discovery and toward a streamlined translation from patient profiling to assays …