Mechanisms of action and clinical application of macrolides as immunomodulatory medications

S Kanoh, BK Rubin - Clinical microbiology reviews, 2010 - journals.asm.org
Macrolides have diverse biological activities and an ability to modulate inflammation and
immunity in eukaryotes without affecting homeostatic immunity. These properties have led to …

Macrolides: from in vitro anti-inflammatory and immunomodulatory properties to clinical practice in respiratory diseases

P Zarogoulidis, N Papanas, I Kioumis… - European journal of …, 2012 - Springer
Background Macrolides have long been recognised to exert immunomodulary and anti-
inflammatory actions. They are able to suppress the “cytokine storm” of inflammation and to …

[HTML][HTML] Fluticasone, azithromycin, and montelukast treatment for new-onset bronchiolitis obliterans syndrome after hematopoietic cell transplantation

KM Williams, GS Cheng, I Pusic, M Jagasia… - Biology of Blood and …, 2016 - Elsevier
Bronchiolitis obliterans syndrome (BOS) after allogeneic hematopoietic cell transplantation
(HCT) is associated with high mortality. We hypothesized that inhaled fluticasone …

British Thoracic Society guideline for the use of long-term macrolides in adults with respiratory disease

D Smith, IA Du Rand, C Addy… - BMJ open …, 2020 - bmjopenrespres.bmj.com
The full British Thoracic Society (BTS) guideline for the use of long-term macrolides in adults
with respiratory disease is published in Thorax. The following is a summary of the …

Major complications following hematopoietic stem cell transplantation

B Afessa, SG Peters - Seminars in respiratory and critical care …, 2006 - thieme-connect.com
Tens of thousands of patients undergo hematopoietic stem cell transplantation (HSCT)
annually, 15 to 40% of whom are admitted to the intensive care unit. Pulmonary …

ERS/EBMT clinical practice guidelines on treatment of pulmonary chronic graft-versus-host disease in adults

S Bos, J Murray, M Marchetti… - European …, 2024 - publications.ersnet.org
Chronic graft-versus-host disease (cGvHD) is a common complication after allogeneic
haematopoietic stem cell transplantation, characterised by a broad disease spectrum that …

Diagnosis and treatment of pulmonary chronic GVHD: report from the consensus conference on clinical practice in chronic GVHD

GC Hildebrandt, T Fazekas, A Lawitschka… - Bone marrow …, 2011 - nature.com
This consensus statement established under the auspices of the German working group on
BM and blood stem cell transplantation (DAG-KBT), the German Society of Hematology and …

Immunomodulatory indications of azithromycin in respiratory disease: a concise review for the clinician

CL Cramer, A Patterson, A Alchakaki… - Postgraduate …, 2017 - Taylor & Francis
Azithromycin has a well-characterized bacteriostatic activity. However, it also has a robust
immunomodulatory effect that has proven beneficial in a variety of chronic illnesses. This …

How I treat bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation

KM Williams - Blood, The Journal of the American Society of …, 2017 - ashpublications.org
In past years, a diagnosis of bronchiolitis obliterans syndrome (BOS) after allogeneic
hematopoietic cell transplant (HCT) conferred nearly universal mortality secondary to lack of …

Bronchiolitis obliterans after allogeneic hematopoietic stem cell transplantation

KM Williams, JW Chien, MT Gladwin, SZ Pavletic - Jama, 2009 - jamanetwork.com
With improvements in supportive care, both long-term survival following allogeneic
hematopoietic stem cell transplantations (HSCTs) and the indications for this procedure …