Time-and lineage-resolved transcriptional profiling uncovers gene expression programs and clonal relationships that underlie human T lineage specification

YS Michaels, MC Major, B Bonham-Carter, J Zhang… - bioRxiv, 2023 - biorxiv.org
T cells develop from multi-potent hematopoietic progenitors in the thymus and provide
adaptive protection against pathogens and cancer. However, the emergence of human T …

[HTML][HTML] Tracking the gene expression programs and clonal relationships that underlie mast, myeloid, and T lineage specification from stem cells

YS Michaels, MC Major, B Bonham-Carter, J Zhang… - Cell Systems, 2024 - cell.com
T cells develop from hematopoietic progenitors in the thymus and protect against pathogens
and cancer. However, the emergence of human T cell-competent blood progenitors and …