Signaling mechanisms regulating endothelial permeability

D Mehta, AB Malik - Physiological reviews, 2006 - journals.physiology.org
The microvascular endothelial cell monolayer localized at the critical interface between the
blood and vessel wall has the vital functions of regulating tissue fluid balance and supplying …

Ribosome biogenesis: emerging evidence for a central role in the regulation of skeletal muscle mass

T Chaillou, TJ Kirby, JJ McCarthy - Journal of cellular …, 2014 - Wiley Online Library
The ribosome is a supramolecular ribonucleoprotein complex that functions at the heart of
the translation machinery to convert mRNA into protein. Ribosome biogenesis is the primary …

The vascular endothelium as a target of cadmium toxicity

WC Prozialeck, JR Edwards, JM Woods - Life sciences, 2006 - Elsevier
Cadmium (Cd) is an important industrial and environmental pollutant that can produce a
wide variety of adverse effects in humans and animals. A growing volume of evidence …

A novel viral mechanism for dysregulation of β-catenin in Kaposi's sarcoma–associated herpesvirus latency

M Fujimuro, FY Wu, C Aprhys, H Kajumbula… - Nature medicine, 2003 - nature.com
The Kaposi's sarcoma–associated herpesvirus (KSHV) latency-associated nuclear antigen
(LANA) is expressed in all KSHV-associated tumors, including Kaposi's sarcoma (KS) and …

Atherosclerosis and cancer: common molecular pathways of disease development and progression

JS Ross, NE Stagliano, MJ Donovan… - Annals of the New …, 2001 - Wiley Online Library
Recently, a series of shared molecular pathways have emerged that have in common a
significant role in the pathogenesis and progression of both atherosclerosis and cancer …

Wnt5a expression is associated with the tumor proliferation and the stromal vascular endothelial growth factor—an expression in non–small-cell lung cancer

C Huang, D Liu, J Nakano, S Ishikawa… - Journal of clinical …, 2005 - ascopubs.org
Purpose The Wnt gene family encodes the multifunctional signaling glycoproteins. We
performed the present study to investigate the clinical significance of Wnt5a expression in …

Presenilin couples the paired phosphorylation of β-catenin independent of axin: implications for β-catenin activation in tumorigenesis

DE Kang, S Soriano, X **a, CG Eberhart… - Cell, 2002 - cell.com
The Alzheimer's disease-linked gene presenilin 1 (PS1) is required for intramembrane
proteolysis of APP and Notch. In addition, recent observations strongly implicate PS1 as a …

Wnt/β-catenin signaling activates growth-control genes during overload-induced skeletal muscle hypertrophy

DD Armstrong, KA Esser - American Journal of Physiology …, 2005 - journals.physiology.org
β-Catenin is a transcriptional activator shown to regulate the embryonic, postnatal, and
oncogenic growth of many tissues. In most research to date, β-catenin activation has been …

Cadherin-bound β-catenin feeds into the Wnt pathway upon adherens junctions dissociation: evidence for an intersection between β-catenin pools

Y Kam, V Quaranta - PloS one, 2009 - journals.plos.org
β-catenin is an essential component of two cellular systems: cadherin-based adherens
junctions (AJ) and the Wnt signaling pathway. A functional or physical connection between …

Cell adhesion and spreading behavior on vertically aligned silicon nanowire arrays

S Qi, C Yi, S Ji, CC Fong, M Yang - ACS applied materials & …, 2009 - ACS Publications
In this report, we studied the interactions between biological cells and vertically aligned
silicon nanowire (SiNW) arrays and focused on how SiNW arrays affected cellular behaviors …