Polymeric delivery of therapeutic nucleic acids
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …
Poly (ethylene glycol) alternatives in biomedical applications
X Yao, C Qi, C Sun, F Huo, X Jiang - Nano Today, 2023 - Elsevier
Abstract Poly (ethylene glycol)(PEG) as gold standard has been extensively conjugated to
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …
diagnostic and therapeutic agents or decorated on the surface of nanoplatforms, which is …
Star polymers
Recent advances in controlled/living polymerization techniques and highly efficient coupling
chemistries have enabled the facile synthesis of complex polymer architectures with …
chemistries have enabled the facile synthesis of complex polymer architectures with …
[HTML][HTML] Copper-mediated living radical polymerization (atom transfer radical polymerization and copper (0) mediated polymerization): from fundamentals to …
The discovery of the first “living” radical polymerization by Otsu and co-workers (1) in 1982
heralded the start of a very exciting time for polymer chemists. Since then, a plethora of living …
heralded the start of a very exciting time for polymer chemists. Since then, a plethora of living …
Co-delivery of drugs and plasmid DNA for cancer therapy
Cancer is an extremely complex disease involving multiple signaling pathways that enable
tumor cells to evade programmed cell death, thus making cancer treatment extremely …
tumor cells to evade programmed cell death, thus making cancer treatment extremely …
Harnessing amphiphilic polymeric micelles for diagnostic and therapeutic applications: Breakthroughs and bottlenecks
Amphiphilic block copolymers are widely utilized in the design of formulations owing to their
unique physicochemical properties, flexible structures and functional chemistry. Amphiphilic …
unique physicochemical properties, flexible structures and functional chemistry. Amphiphilic …
Recent progress in nanomaterials for gene delivery applications
Nanotechnology-based gene delivery is the division of nanomedicine concerned with the
synthesis, characterization, and functionalization of nanomaterials to be used in targeted …
synthesis, characterization, and functionalization of nanomaterials to be used in targeted …
A facile-synthesized star polycation constructed as a highly efficient gene vector in pest management
J Li, J Qian, Y Xu, S Yan, J Shen… - … Sustainable Chemistry & …, 2019 - ACS Publications
Gene vectors have been extensively applied in various fields. However, the high economic
cost of gene vectors limits their development and application, and there is an urgent demand …
cost of gene vectors limits their development and application, and there is an urgent demand …
Recent advances of zwitterionic-based topological polymers for biomedical applications
M Zhang, P Yu, J **e, J Li - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Zwitterionic polymers, comprising hydrophilic anionic and cationic groups with the same
total number of positive and negative charges on the same monomer residue, have received …
total number of positive and negative charges on the same monomer residue, have received …
Redox‐responsive and drug‐embedded silica nanoparticles with unique self‐destruction features for efficient gene/drug codelivery
Q Zhang, C Shen, N Zhao, FJ Xu - Advanced Functional …, 2017 - Wiley Online Library
The development of advanced gene/drug codelivery carriers with stimuli‐responsive release
manner for complementary cancer therapy is desirable. In this study, novel disulfide‐bridged …
manner for complementary cancer therapy is desirable. In this study, novel disulfide‐bridged …