Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs)
are widely expressed and have key roles in gene regulation. Recent studies have begun to …

Since the introduction of the central dogma of molecular biology in 1958, various RNA
species have been discovered. Messenger RNAs transmit genetic instructions from DNA to …

Long non-coding ribonucleic acids (RNAs)(lncRNAs) are key players in tumorigenesis and
immune responses. The nature of their cell type-specific gene expression and other …

Gene maps, or annotations, enable us to navigate the functional landscape of our genome.
They are a resource upon which virtually all studies depend, from single-gene to genome …

Breast cancer is the most common cancer, and the second cause of cancer-related deaths
(after lung cancer) among women. Develo** tumor metastasis and invasion is the most …

The long non-coding RNAs (lncRNAs) are the crucial regulators of human chronic diseases.
Therefore, approaches such as antisense oligonucleotides, RNAi technology, and small …

Long non-coding RNAs (lncRNAs) are a growing focus of cancer genomics studies, creating
the need for a resource of lncRNAs with validated cancer roles. Furthermore, it remains …

Abstract Background The RTK/PI3K/AKT pathway plays key roles in the development and
progression of many cancers, including GBM. As a regulatory molecule and a potential drug …

Long non-coding RNAs (lncRNAs) represent a huge reservoir of potential cancer targets.
Such" onco-lncRNAs" have resisted traditional RNAi methods, but CRISPR-Cas9 genome …

RNA therapeutics (RNATx) aim to treat diseases, including cancer, by targeting or
employing RNA molecules for therapeutic purposes. Amongst the most promising targets …