WikiPathways 2024: next generation pathway database
WikiPathways (wikipathways. org) is an open-source biological pathway database.
Collaboration and open science are pivotal to the success of WikiPathways. Here we …
Collaboration and open science are pivotal to the success of WikiPathways. Here we …
PathDIP 5: improving coverage and making enrichment analysis more biologically meaningful
Abstract Pathway Data Integration Portal (PathDIP) is an integrated pathway database that
was developed to increase functional gene annotation coverage and reduce bias in …
was developed to increase functional gene annotation coverage and reduce bias in …
Inference of differential key regulatory networks and mechanistic drug repurposing candidates from scRNA-seq data with SCANet
Motivation The reconstruction of small key regulatory networks that explain the differences in
the development of cell (sub) types from single-cell RNA sequencing is a yet unresolved …
the development of cell (sub) types from single-cell RNA sequencing is a yet unresolved …
MetalinksDB: a flexible and contextualizable resource of metabolite-protein interactions
From the catalytic breakdown of nutrients to signaling, interactions between metabolites and
proteins play an essential role in cellular function. An important case is cell–cell …
proteins play an essential role in cellular function. An important case is cell–cell …
[HTML][HTML] ODAMNet: A Python package to identify molecular relationships between chemicals and rare diseases using overlap, active module and random walk …
Environmental factors are external conditions that can affect the health of living organisms.
For a number of rare genetic diseases, an interplay between genetic and environmental …
For a number of rare genetic diseases, an interplay between genetic and environmental …
Pan-cancer proteogenomic landscape of whole-genome doubling reveals putative therapeutic targets in various cancer types
Background: Whole-genome doubling (WGD) is prevalent in cancer and drives tumor
development and chromosomal instability. Driver mutations in mitotic cell cycle genes and …
development and chromosomal instability. Driver mutations in mitotic cell cycle genes and …
[PDF][PDF] VISPER-Visualization System for Interactions between Proteins and Drugs for Exploratory Research
D Dehncke, V Fiebach, L Kinzel, K Baumann… - 2024 - diglib.eg.org
VISPER is a web-based application that enables users to interactively explore and analyze
drug-protein associations. Its uniqueness lies in the dataset for which it has been specifically …
drug-protein associations. Its uniqueness lies in the dataset for which it has been specifically …
DysRegNet: Patient-specific and confounder-aware dysregulated network inference
Gene regulation is frequently altered in diseases in unique and often patient-specific ways.
Hence, personalized strategies have been proposed to infer patient-specific gene-regulatory …
Hence, personalized strategies have been proposed to infer patient-specific gene-regulatory …