Grass carp (Ctenopharyngodon idella) is a highly productive freshwater fish species that
annually contributes significant economic value to the aquaculture industry. However, its …

Teleost fish type I IFNs and the associated receptors from the cytokine receptor family B
(CRFB) are characterized by remarkable diversity and complexity. How the fish type I IFNs …

Suppressors of cytokine signaling (SOCS) proteins are important regulators of the Janus
kinase-signal transducer and activator of transcription (JAK-STAT) pathway. Within the …

Type IV interferon (IFN) has been shown to be a cytokine with antiviral activity in fish and
amphibian. But, it has not been cloned and characterized functionally in avian species. In …

The class II cytokine receptor family members are receptors of class 2 helical cytokines in
mammals, and are named cytokine receptor family B (CRFB) in fish. In zebrafish, sixteen …

In aquaculture, viral diseases pose a significant threat and can lead to substantial economic
losses. The primary defense against viral invasion is the innate immune system, with …

Teleost fish possess a diversity of type Ⅰ interferons (IFNs) repertoire, which play a crucial
role in antiviral and antimicrobial immune responses. In our previous study, IFNe1-3 and …

Interferons (IFNs) are a group of secreted cytokines that play a crucial role in antiviral
immunity. Type I IFNs display functional disparities. In teleosts, type I IFNs are categorized …

Golden pompano, Trachinotus ovatus, is a perciform fish with great economic value and is
widely cultured in the coastal areas of China. The wide occurrence of bacterial, parasitic and …

As one member of type I IFN, IFNd showed huge distinctive responses and activity during
the viral or bacterial infection in various fish species. Our previous study identified IFNd from …