Conspectus Stereodefined aliphatic heterocycles are one of the fundamental structural
motifs observed in natural products and biologically active compounds. Various strategies …

For the purpose of this article, iminosugars are polyhydroxylated secondary and tertiary
amines in which the molecules resemble monosaccharide sugars in which the ring oxygen …

In the past few decades, our understanding of glycan information‐encoding power has
notably increased, thus leading to a significant growth also in the design and synthesis of …

It has been amply constated that sugar ligand multivalency increases lectin-binding avidities
dramatically, thereby modulating the capacity of carbohydrates to participate in …

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease, which is characterized by
hyperglycemia, chronic insulin resistance, progressive decline in β-cell function, and defect …

Carbohydrates are of great importance in a variety of biological processes, including but not
limited to, energy production, energy storage, protein recognition, immune response, and …

Lysosomal storage disorders (LSDs) are often caused by mutations that destabilize native
folding and impair the trafficking of enzymes, leading to premature endoplasmic reticulum …

The importance of glycosidase inhibitors and especially the bicyclic molecules has led to
design and assessment of many analogs of naturally occurring molecules. This review …

The use of noncovalent interactions (NCIs) has received significant attention as a pivotal
synthetic handle. Recently, the exploitation of unconventional NCIs has gained considerable …

Iminosugars are naturally occurring carbohydrate analogues known since 1967. These
natural compounds and hundreds of their synthetic derivatives prepared over five decades …