Despite advances in molecular biology, genetics, computation, and medicinal chemistry,
infectious disease remains an ominous threat to public health. Addressing the challenges …

The spread of bacterial drug resistance has posed a severe threat to public health globally.
Here, we cover bacterial resistance to current antibacterial drugs, including traditional herbal …

Antimicrobial peptides (AMPs) hold promise as alternatives to traditional antibiotics for
preventing and treating multidrug-resistant infections. Although they have potent …

Despite significant progress in antibiotic discovery, millions of lives are lost annually to
infections. Surprisingly, the failure of antimicrobial treatments to effectively eliminate …

Introduction As machine learning (ML) and artificial intelligence (AI) expand to many
segments of our society, they are increasingly being used for drug discovery. Recent deep …

The design choices underlying machine-learning (ML) models present important barriers to
entry for many biologists who aim to incorporate ML in their research. Automated machine …

Diabetes mellitus has become a major public health concern associated with high mortality
and reduced life expectancy and can cause blindness, heart attacks, kidney failure, lower …

Peptide‐based drugs offer high specificity, potency, and selectivity. However, their inherent
flexibility and differences in conformational preferences between their free and bound states …

In recent years, multidrug-resistant pathogenic microorganisms (MDROs) have emerged as
a severe threat to human health, exhibiting robust resistance to traditional antibiotics. This …

Classical plant breeding methods are limited in their ability to confer disease resistance on
plants. However, in recent years, advancements in molecular breeding and biotechnological …