KLF2 in regulation of NF-κB-mediated immune cell function and inflammation
KLF2 (Kruppel-like factor 2) is a member of the zinc finger transcription factor family, which
critically regulates embryonic lung development, function of endothelial cells and …
critically regulates embryonic lung development, function of endothelial cells and …
Fighting the fire: mechanisms of inflammatory gene regulation by the glucocorticoid receptor
L Escoter-Torres, G Caratti, A Mechtidou… - Frontiers in …, 2019 - frontiersin.org
For many decades, glucocorticoids have been widely used as the gold standard treatment
for inflammatory conditions. Unfortunately, their clinical use is limited by severe adverse …
for inflammatory conditions. Unfortunately, their clinical use is limited by severe adverse …
Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis
Background Active pulmonary tuberculosis is difficult to diagnose and treatment response is
difficult to effectively monitor. A WHO consensus statement has called for new non-sputum …
difficult to effectively monitor. A WHO consensus statement has called for new non-sputum …
Epigallocatechin-3-gallate inhibits osteoclastic differentiation by modulating mitophagy and mitochondrial functions
A natural plant product, epigallocatechin-3-gallate (EGCG), was evaluated for its
effectiveness in the regulation of osteoclastogenesis. We found that EGCG inhibited the …
effectiveness in the regulation of osteoclastogenesis. We found that EGCG inhibited the …
[HTML][HTML] Orexin-A alleviates astrocytic apoptosis and inflammation via inhibiting OX1R-mediated NF-κB and MAPK signaling pathways in cerebral ischemia …
D Xu, T Kong, Z Shao, M Liu, R Zhang, S Zhang… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Orexin-A (OXA) is a neuropeptide with neuroprotective effect by reducing cerebral
ischemia/reperfusion injury (CIRI). Inflammation and apoptosis mediated by astrocyte …
ischemia/reperfusion injury (CIRI). Inflammation and apoptosis mediated by astrocyte …
KLF2 (kruppel-like factor 2 [lung]) regulates osteoclastogenesis by modulating autophagy
Macroautophagy/autophagy is involved in myeloid cellular repair, destruction, and
osteoclast differentiation; conversely, KLF2 (kruppel-like factor 2 [lung]) regulates myeloid …
osteoclast differentiation; conversely, KLF2 (kruppel-like factor 2 [lung]) regulates myeloid …
[HTML][HTML] KLF2 regulates dental pulp-derived stem cell differentiation through the induction of mitophagy and altering mitochondrial metabolism
To define the regulatory role of Kruppel-like factor 2 (KLF2) during osteoblast (OB)
differentiation of dental pulp-derived stem cell (DPSC) s, herein, we show that the levels of …
differentiation of dental pulp-derived stem cell (DPSC) s, herein, we show that the levels of …
Regulation of differentiation and generation of osteoclasts in rheumatoid arthritis
Q Niu, J Gao, L Wang, J Liu, L Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Introduction Rheumatoid arthritis (RA), which affects nearly 1% of the world's population, is a
debilitating autoimmune disease. Bone erosion caused by periarticular osteopenia and …
debilitating autoimmune disease. Bone erosion caused by periarticular osteopenia and …
Transcription factor KLF2 and its role in the regulation of inflammatory processes
KT Turpaev - Biochemistry (Moscow), 2020 - Springer
KLF2 is a member of the Kruppel-like transcription factor family of proteins containing highly
conserved DNA-binding zinc finger domains. KLF2 participates in the differentiation and …
conserved DNA-binding zinc finger domains. KLF2 participates in the differentiation and …
Krüppel-like factor 2 (KLF2) in immune cell migration
J Wittner, W Schuh - Vaccines, 2021 - mdpi.com
Krüppel-like factor 2 (KLF2), a transcription factor of the krüppel-like family, is a key regulator
of activation, differentiation, and migration processes in various cell types. In this review, we …
of activation, differentiation, and migration processes in various cell types. In this review, we …