Bioorthogonal chemistry

SL Scinto, DA Bilodeau, R Hincapie, W Lee… - Nature Reviews …, 2021 - nature.com
Bioorthogonal chemistry represents a class of high-yielding chemical reactions that proceed
rapidly and selectively in biological environments without side reactions towards …

Advanced bottom‐up engineering of living architectures

VM Gaspar, P Lavrador, J Borges… - Advanced …, 2020 - Wiley Online Library
Bottom‐up tissue engineering is a promising approach for designing modular biomimetic
structures that aim to recapitulate the intricate hierarchy and biofunctionality of native human …

Enabling In Vivo Photocatalytic Activation of Rapid Bioorthogonal Chemistry by Repurposing Silicon-Rhodamine Fluorophores as Cytocompatible Far-Red …

C Wang, H Zhang, T Zhang, X Zou… - Journal of the …, 2021 - ACS Publications
Chromophores that absorb in the tissue-penetrant far-red/near-infrared window have long
served as photocatalysts to generate singlet oxygen for photodynamic therapy. However, the …

An injectable click-crosslinked hyaluronic acid hydrogel modified with a BMP-2 mimetic peptide as a bone tissue engineering scaffold

SH Park, JY Park, YB Ji, HJ Ju, BH Min, MS Kim - Acta Biomaterialia, 2020 - Elsevier
An injectable, click-crosslinking (Cx) hyaluronic acid (HA) hydrogel scaffold modified with a
bone morphogenetic protein-2 (BMP-2) mimetic peptide (BP) was prepared for bone tissue …

Hyaluronic acid‐based injectable hydrogels for wound dressing and localized tumor therapy: a review

X Yang, B Wang, D Peng, X Nie, J Wang… - Advanced …, 2022 - Wiley Online Library
Hyaluronic acid (HA)‐based hydrogels are regarded as ideal candidates for wound dressing
and localized cancer treatment due to the excellent biocompatibility, potential targeting …

Glycopolymer and poly (β-amino ester)-based amphiphilic block copolymer as a drug carrier

EL Sahkulubey Kahveci, MU Kahveci, A Celebi… - …, 2022 - ACS Publications
Glycopolymers are synthetic macromolecules having pendant sugar moieties and widely
utilized to target cancer cells. They are usually considered as a hydrophilic segment of …

Surface patterning of hydrogel biomaterials to probe and direct cell–matrix interactions

BG Munoz‐Robles, I Kopyeva… - Advanced Materials …, 2020 - Wiley Online Library
Due to their mechanical and structural similarity to native tissues, hydrogel biomaterials
have gained tremendous popularity for applications in 3D tissue culture, therapeutic …

Biofabrication strategies and engineered in vitro systems for vascular mechanobiology

S Pradhan, OA Banda, CJ Farino… - Advanced …, 2020 - Wiley Online Library
The vascular system is integral for maintaining organ‐specific functions and homeostasis.
Dysregulation in vascular architecture and function can lead to various chronic or acute …

Artificial extracellular matrix composed of heparin-mimicking polymers for efficient anticoagulation and promotion of endothelial cell proliferation

H Wang, J Wang, J Feng, Y Rao, ZY Xu… - … Applied Materials & …, 2022 - ACS Publications
Heparin-mimicking polymers have emerged as an alternative to heparin to construct
effective and safe anticoagulant surfaces. However, the present heparin-mimicking polymers …

Matrix adhesiveness regulates myofibroblast differentiation from vocal fold fibroblasts in a bio-orthogonally cross-linked hydrogel

J Song, H Gao, H Zhang, OJ George… - … applied materials & …, 2022 - ACS Publications
Repeated mechanical and chemical insults cause an irreversible alteration of extracellular
matrix (ECM) composition and properties, giving rise to vocal fold scarring that is refractory …